It has been known for decades that human Lyme disease is caused by the three spirochete species Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. Recently, Borrelia valaisiana, Borrelia spielmanii, and Borrelia bissettii have been associated with Lyme disease. We report the complete genome sequences of B. valaisiana VS116, B. spielmanii A14S, and B. bissettii DN127.

Borrelia burgdorferi sensu lato, the spirochete that causes human Lyme borreliosis (LB), is a genetically and phenotypically divergent species. In the past several years, various molecular approaches have been developed and used to determine the phenotypic and genetic heterogeneity within the LB-related spirochetes and their potential association with distinct clinical syndromes. These methods ...

A total of 874 Ixodes ricinus ticks were collected in Switzerland to investigate the genetic diversity of the Borrelia population. We integrated to the RT-PCR method the DNA sequence analysis of a 162-bp fragment of the recA gene. Five genospecies were detected: Borrelia afzelii, Borrelia burgdorferi s.s., Borrelia garinii, Borrelia valaisiana, and Borrelia lusitaniae. A heterogeneous distribut...

background: a molecular survey was conducted to investigatethe presence of pathogenic borrelia persica species caus­ing the tick borne relapsing fever (tbrf) in takistan district qazvin province, western iran. methods: a number of 1021 s oft ticks were collected from 31 villages including previously reported infected and none-infected tbrf cases and individually examined for the presenceof b. p...

Spirochetes in the genus Borrelia are responsible for tick-borne relapsing fever and Lyme disease. Borrelia-tick interactions are highly specific as each species of Borrelia is only transmitted by one or a few closely related species of ticks. Borrelia colonize the gut or salivary glands of ticks. Several Borrelia genes required for tick colonization or transmission have been identified. Borrel...

objective: relapsing fever caused by borrelia persica is an acute tick-borne disease which is transmitted by soft ticks of ornithodoros tholozani to human. the disease is reported from middle east and many regions of iran. detection of infection is problematic since the suspected infected ticks should be fed on animal hosts such as guinea pigs and subsequently after 7-14 days, the animal blood ...