cotC requires the transcription factor CudA for its expression in the posterior, prespore cells of the slug, while the expL7 gene requires CudA for its expression in the anterior, tip-organiser region. In order to identify additional transcription factors that might mediate tip-organiser specific expression, we performed affinity chromatography on slug nuclear extracts. The affinity matrix bore...

CudA, a nuclear protein required for Dictyostelium prespore-specific gene expression, binds in vivo to the promoter of the cotC prespore gene. A 14 nucleotide region of the cotC promoter binds CudA in vitro and ECudA, an Entamoeba CudA homologue, also binds to this site. The CudA and ECudA DNA-binding sites contain a dyad and, consistent with a symmetrical binding site, CudA forms a homodimer i...

Motion estimation is currently the most computationally intensive portion of the H.264 encoding process. Previous attempts to parallelize this algorithm in CUDA 1 showed sizable speedups but sacrificed quality by ignoring the motion vector prediction (MVp). We demonstrate the viability of a hierarchical (pyramid) motion estimation algorithm in CUDA. This solution addresses the MVp problem while...

The CUDA programming model, which is based on an extended ANSI C language and a runtime environment, allows the programmer to specify explicitly data parallel computation. NVIDIA developed CUDA to open the architecture of their graphics accelerators to more general applications, but did not provide an efficient mapping to execute the programming model on any other architecture. This document de...

The Dictyostelium cudA gene encodes a nucleoplasmic protein that is essential for normal culmination. There are no functionally characterised homologues in other organisms but there is a related gene of unknown function in Entamoeba histolytica. The cudA gene is expressed by the prestalk cells that constitute the slug tip (the pstA cells), it is not detectably expressed in the band of prestalk ...

The tip of the Dictyostelium slug functions much like an embryonic organiser; when grafted onto the flank of a recipient slug, it recruits a mass of prespore cells and leads them away as part of a secondary slug. CudA is a nuclear protein which is expressed in prespore cells where it acts as a specific transcription factor. CudA is also expressed in an anteriorly located group of cells, the tip...

The proliferation of heterogeneous computing systems has led to increased interest in parallel architectures and their associated programming models. One of the most promising models for heterogeneous computing is the accelerator model, and one of the most cost-e↵ective, high-performance accelerators currently available is the general-purpose, graphics processing unit (GPU). Two similar program...

CUDA programmed GPUs are rapidly becoming a major choice in high performance computing and there are a growing number of applications which are being ported to the CUDA platform. However much less research has been carried out to evaluate the performance when CUDA is integrated with other parallel programming paradigms. We have developed a general purpose matrix multiplication algorithm and a C...