the purpose of the present study was to determine the tropane alkaloid content of four hyoscyamus species from iran, i.e. h. pusillus l., h. niger l., h. reticulatus l. and h. kurdicus bornm. determination of alkaloids was performed by the hplc method. samples were extracted with chloroform-methanol-25% ammonium hydroxide 15:5:1 (v/v/v). hplc separation was performed on eurospher c18 reversed p...

The purpose of the present study was to determine the tropane alkaloid content of four Hyoscyamus species from Iran, i.e. H. pusillus L., H. niger L., H. reticulatus L. and H. kurdicus Bornm. Determination of alkaloids was performed by the HPLC method. Samples were extracted with chloroform-methanol-25% ammonium hydroxide 15:5:1 (V/V/V). HPLC separation was performed on Eurospher C18 reversed p...

In this present cardioprotective activity study the crude powder of the Hyoscyamus niger Linn is administered to the male albino rats at the dose of 100mg/100g.b.wt. The markers of cardiac function test assess the normal functioning of heart. If there is a change in their normal values of these makers it indicates the dysfunction of heart. Biochemical parameters like TGL, Ck-MB and LPO were car...

background and objective: recent studies have shown that anticholinergic alkaloids compounds have strong analgesic effects. due to presence of anticholinergic alkaloids in hyoscyamus niger and its mentioned effects in iranian traditional medicine, its analgesic effects were assessed. at first, acute and chronic pain thresholds in male nmri rats with formalin test was evaluated, then oral and in...

Effects of Hyoscyamus niger L on central nervous system have been known for many years. The effects of methanolic extract of H. niger L. on seizures induced by picrotoxin was studied in mice in this investigation. In this study 7 groups of animals pretreated with methanolic extract of the plant (12.5, 25, 50, 100, 200, 300, 400 mg/kg/i.p.), 20 minutes prior to the picrotoxin (12 mg/kg/ i.p.)--i...