نتایج جستجو برای: ایستگاه cng

تعداد نتایج: 16003  

Journal: :Neuron 1995
Stephan Frings Reinhard Seifert Matthias Godde U.Benjamin Kaupp

Sensory transduction in vertebrate photoreceptors and olfactory sensory neurons is mediated by cyclic nucleotide-gated (CNG) channels that conduct mono- and divalent cations. Ca2+ entering the cell through CNG channels intimately controls signaling pathways by regulating several key enzymes. Cloned CNG channels from photoreceptors and olfactory sensory neurons profoundly differ in their relativ...

Journal: :The Journal of antibiotics 1993
M Kawatsu T Yamashita M Osono T Masuda M Ishizuka T Takeuchi

Antitumor effects and function of T cells in tumor bearing mice given conagenin (CNG), a low molecular immunomodulator, were investigated. The administration of CNG, once a week for 4 weeks, was the most effective schedule in inhibiting growth of IMC carcinoma, a syngeneic tumor. In this regimen, cytotoxic T lymphocytes and natural killer activities in spleens of CNG treated mice were maintaine...

Journal: :Physiological reviews 2002
U Benjamin Kaupp Reinhard Seifert

Cyclic nucleotide-gated (CNG) channels are nonselective cation channels first identified in retinal photoreceptors and olfactory sensory neurons (OSNs). They are opened by the direct binding of cyclic nucleotides, cAMP and cGMP. Although their activity shows very little voltage dependence, CNG channels belong to the superfamily of voltage-gated ion channels. Like their cousins the voltage-gated...

2014
Zia Wadud

Motor vehicles are one of the major sources of air pollution in Dhaka, the capital of Bangladesh. The government took various policies to convert the petroleum vehicles on road to run on compressed natural gas (CNG), which allows both air quality improvements and energy security benefits. One of the market friendly policies to encourage the fuel switch was to increase the price differential bet...

2015
Min Hwan Kim Soohyeon Lee Ja Seung Koo Kyung Hae Jung In Hae Park Joon Jeong Seung Il Kim Seho Park Hyung Seok Park Byeong-Woo Park Joo-Hang Kim Joohyuk Sohn

BACKGROUND Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer, and its molecular pathogenesis still remains to be elucidated. This study aimed to evaluate the prevalence and implication of anaplastic lymphoma kinase (ALK) copy number change in IBC patients. METHODS We retrospectively collected formalin-fixed, paraffin-embedded tumor tissues and medical records of IB...

2012
Peter C. Meighan Starla E. Meighan Elizabeth D. Rich R. Lane Brown Michael D. Varnum

Photoreceptor cyclic nucleotide-gated (CNG) channels are the principal ion channels responsible for transduction of the light-induced change in cGMP concentration into an electrical signal. The ligand sensitivity of photoreceptor CNG channels is subject to regulation by intracellular signaling effectors, including calcium-calmodulin, tyrosine kinases and phosphoinositides. Little is known, howe...

Journal: :The Journal of General Physiology 2003
Johannes Reisert Paul J. Bauer King-Wai Yau Stephan Frings

Odorants activate sensory transduction in olfactory receptor neurons (ORNs) via a cAMP-signaling cascade, which results in the opening of nonselective, cyclic nucleotide-gated (CNG) channels. The consequent Ca2+ influx through CNG channels activates Cl channels, which serve to amplify the transduction signal. We investigate here some general properties of this Ca-activated Cl channel in rat, as...

2018
Stylianos Michalakis Elvir Becirovic Martin Biel

The first step in vision is the absorption of photons by the photopigments in cone and rod photoreceptors. After initial amplification within the phototransduction cascade the signal is translated into an electrical signal by the action of cyclic nucleotide-gated (CNG) channels. CNG channels are ligand-gated ion channels that are activated by the binding of cyclic guanosine monophosphate (cGMP)...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1997
J Bradley Y Zhang R Bakin H A Lester G V Ronnett K Zinn

Cyclic nucleotide-gated (cng) channels are important components of signaling systems mediating sensory transduction. In vertebrate photoreceptors, light activates a signaling cascade that causes a decrease in intracellular cGMP concentrations, closing retinal cng channels. Signal transduction in olfactory receptor neurons is believed to proceed via G-protein-mediated elevation of intracellular ...

2001
Anil Singh Niraj Sharma Kirti Sharma Chander Bhan

Road transportation has most adversely affected the air quality in Delhi. The existing fleet of 3.5 million motor vehicles in Delhi contributes nearly 70% of the total air pollution load. To improve the air quality status in Delhi various measures viz. improvement in fuel quality and engine technology, use of exhaust treatment devices, use of cleaner alternative fuels (CNG) etc. have been adopt...

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