for a long time, scientists have tried to describe disorders just by genetic or environmental factors. however, the role of epigenetics in human diseases has been considered from a half of century ago. in the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

objective: in this paper, we have introduced topoisomerase inhibitors, mechanism of action and types of them. dna topoisomerases are ubiquitous enzymes that catalyze essential enzymes to solve the topological problems accompanying key nuclear processes such as dna replication, transcription, repair and chromatin assembly by introducing temporary single or double strand breaks in the dna. result...

all wasp species in the genus lysiphlebus fã¶rster are solitary endoparasitoids of aphids andconsidered a taxonomically difficult group. in this study a part of coi and its2 was used to distinguishtwo closely related species l. fabarum (marshall) and l. confusus tremblay & eady in iran. thesequencing with a similarity about 99.5% showed coi's inability to separate the species l. fabarum an...

two nuclear microsatellite dna loci along with partial sequences of mitochondrial dna trna pro -d-loop region were analyzed to assess the genetic diversity and population genetic structure of spottybelly greenling ( hexagrammos agrammus ). a total of 85 individuals were investigated from two different locations at the east and the south coasts of korea which are imwonjin (im) and tongyeong (tn)...

background: infestation of the skin by the “itch mite” sarcoptes scabiei var. hominis results in a contagious skin infection in humans called “sca-bies”. by resolving morphology issues, the present study was designed to be acquainted with itch mite by molecular markers. methods: the mite samples were collected from scabies patients by visiting government hospitals of twin city, pakistan. for su...

background: extraction of blood genomicdnais one of the main approaches for clinical and molecular biology studies. although several methods have been developed for extraction of blood genomic dna, most of these methods consume long time and use expensive chemicals such as proteinase k and toxic organic solvent such as phenol and chloroform. the objective of this study was to developed easy and...