Aloperine (ALO) exhibits neuroprotective effects against oxidative stress in vitro; however, its protective effect in early brain injury (EBI) following experimental subarachnoid hemorrhage (SAH) remains to be elucidated. The aim of the current study was to evaluate the antioxidant activity of ALO in EBI, and its association with nuclear factor erythroid-related factor 2 and the antioxidant res...

Single crystals of the title compound, K(2)Al(2)P(8)O(24), were obtained by solid-state reaction. The monoclinic structure is isotypic with that of the Ga(III) analogue and is built of eight-membered phosphate ring anions P(8)O(24) (8-) (2/m symmetry) isolated from each other and further linked by isolated AlO(6) octa-hedra ( symmetry) by sharing corners. Each AlO(6) octa-hedron is linked to fo...

UNLABELLED ALO-01 (EMBEDA [morphine sulfate and naltrexone hydrochloride] extended-release capsules [King Pharmaceuticals, Inc, Bridgewater, NJ]), indicated for chronic moderate-to-severe pain, is designed to release naltrexone upon tampering (eg, by crushing), reducing morphine-induced subjective effects. This multicenter, randomized, double-blind, crossover study assessed pharmacokinetics, ef...

Two virulence factors of Listeria monocytogenes, listeriolysin O (LLO) and phosphatidylinositol-specific phospholipase C (PI-PLC), mediate escape of this pathogen from the phagocytic vacuole of macrophages, thereby allowing the bacterium access to the host cell cytosol for growth and spread to neighboring cells. We characterized their orthologs from Bacillus anthracis by expressing them in L. m...

Gastric lipase (GL) plays an important role in emulsification and digestion of food fat. Lipids are components of the hydrophobic mucus and mucosa barrier. Damage of the gastric mucosa may therefore be related to changes in the lipid content and GL activity. In the present paper, we studied the effect of administration of a single dose of 96 % ethanol (E) and indomethacin 20 mg x kg(-1) (IND) o...

An immobilized amino acid napbthylamide substrate for proteinases with tryptic-like specificity was prepared by reacting L-arginine P-naphthylamide with an N-hydroxysuccinimide-activated derivative of agarose. Hydrolysis of the immobilized substrate (AlO-Arg-PNA) was followed by monitoring the increase in fluorescence accompanying the release of /3-naphthylamine. Assays using AIO-Arg-PNA were d...

Resistive switching memory cross-point arrays with TiN/HfO x /AlO y /Pt structure were fabricated. The bi-layered resistive switching films of 5-nm HfO x and 3-nm AlO y were deposited by atomic layer deposition (ALD). Excellent device performances such as low switching voltage, large resistance ratio, good cycle-to-cycle and device-to-device uniformity, and high yield were demonstrated in the f...

morphologies. The structural integrity of the CH 3-SAMs was also found to be disturbed substantially at the onset of the ALD process with H 2 O. In order to improve the surface morphology of AlO x on CH 3-SAM surfaces, a two-stage ALD process was developed. In the two-stage ALD process for AlO x , the first stage utilized n-propanol as the oxygen source and the second stage proceeded with H 2 O...

PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the allogenic transplant (ALO, BALB/c mice, n=24). In each group, the animals were distributed with and without IPC-R. It was obtained the following subgroups: Tx, IPC-R, Fk, IPC-F...

eBay is by far the world’s largest online auction site. Millions of people are doing transactions through it. eBay offers the sellers several additional listing options (“ALO” for short) at certain prices for them to enhance the visibility or attractiveness of their auction listings. In this paper we tried to find out how much these ALO can help to improve the outcome of an online auction, focu...