The ground-breaking discovery of the reprogramming of somatic cells into pluripotent cells, termed induced pluripotent stem cells (iPSCs), was accomplished by delivering 4 transcription factors, Oct4, Sox2, Klf4, and c-Myc, into fibroblasts. Since then, several efforts have attempted to unveil other factors that are directly implicated in or might enhance reprogramming. Importantly, a number of...

The period of postnatal development in the edible dormouse occurs before hibernation, causing a restricted growth. Four stages can be identified according to morphological and behavior nesting period. Dormice are born completely naked, unable move independently. During second stage (11–21 days), juveniles acquire variety movements. third (22–30 days) begins with opening eyes is associated activ...

The Edible Dormouse ( Glis glis) uses different types of shelters at particular times the year. During hibernation, they are found in underground cavities or sometimes caves, while during active periods mostly use above-ground shelters: tree hollows nest boxes. Selection such thermally varied is result physiological requirements both and non-active periods, choosing a lower constant temperature...

The study aimed to determine when, during summer activity, males and females of the edible dormouse most often used loud calls. On this basis, an attempt was made main purpose emission these It assumed that 1) if have calls in July, their emissions may be related primarily mating behaviour (which takes place period), they August, are likely concerned defence food resources, 2) females, vocaliza...

In the UK Edible Dormouse is a non-native pest occurring in c.1000 sq.km of Chilterns area, west London, but it spreading. It causes damage to biota woodlands and also increasingly present within buildings. Licenced humane culling (killing) allowed illegal release them if captured alive. Poisoning illegal. Several thousand are culled buildings annually. The results capture trials adult Glis our...

We consider the problem of identifying diseaseassociated genomic regions in genome-wide association studies (GWAS). It is shown that conventional single SNP analysis can be greatly improved by (i) exploiting the spatial dependency and (ii) conducing set-wise analysis. The SNP set association problem can be conceptualized as the problem of simultaneously testing a large number of sets of hypothe...