Osteosarcoma, the most common bone cancer, leads to a poor survival rate of patients. Drug targeting employing hydroxyapatite (HAp)-based nanocarriers represents fascinating choice for non-invasive treatment osteosarcoma.

Osteosarcoma of the foot is exceedingly uncommon, and as a result, very little known about patient tumor characteristics. In addition, prognosis may be grim due to delayed presentation misdiagnosis. A diagnosis osteosarcoma, regardless location, not only reduce long-term survival but also modify treatment plan, resulting in less favorable functional cosmetic outcomes. Here we report diagnostic ...

Osteosarcoma is relatively rare in the jaws and variable in presentation, thus its recognition may be quite confusing and delay diagnosis and treatment. Also, in contrast to most malignancies, osteosarcoma is usually encountered earlier in life and may clinically resemble features of more common oral entities such as chronic osteomyelitis, fibrous dysplasia, osteoblastic metastatic carcinom...

Osteosarcoma (osteogenic sarcoma: OS) is the most common primary malignant bone tumor of long bones, whereas primary osteosarcoma of chest wall, especially in sternum, is extremely rare. We report a 57-year-old man with an immobile slow growing mass located in the middle of the sternum. The patient had no significant pain or tenderness and the past medical history was not remarkable. CT-scan sh...

epitheloid osteosarcoma (carcinosarcoma) of the bone is a rare malignant tumor and only a few cases have been reported in the literature. in this study, we report two cases of osseous carcinosarcoma (epitheloid osteosarcoma) with immunohistochemical studies.  the morphological and immunohistochemical data in these two cases support the theory of divergent differentiation of primitive, uncommitt...

Giant cell-rich osteosarcoma of the jaw (JGCRO) is very rare but it diagnostically important because its poor prognosis compared to other variants osteosarcoma. We report a case recurrent JGCRO initially diagnosed as an ossifying fibroma. The clinical presentation, radiologic and histologic features intermediate outcome treatment are highlighted.

osteosarcoma (os) is a malignant mesenchymal tumor, which rarely occurs in the maxilla. although variable histologic and radiographic features of os have been reported previously, in the majority of the cases painful swelling of the jaw is mentioned as the first clinical presentation. furthermore, early diagnosis and wide surgical resection of the tumor are the most important determinant factor...

1. Abstract 2. Introduction 3. PET/CT in the diagnosis of osteosarcoma 3.1. PET/CT in the diagnosis of pediatric osteosarcoma 3.2. PET/CT in the differential diagnosis between osteosarcoma and mimic diseases 3.3. PET/CT in the diagnosis of rare cases 4. PET/CT in the relapse of osteosarcoma 5. PET/CT in the metastases of osteosarcoma 6. PET/CT in the histological response to neoadjuvant chemoth...

Background & Aims: Osteosarcoma is one of the most prevalent malignant bone tumors . This study is designed to assess the prognostic effect of pathologic fracture and treatment options on survival of patients with osteosarcoma. Materials & Methods: In this study, prognosis of 106 patients with limb osteosarcoma, which were treated at three  hospitals in Tehran from April to August 2012 ...

osteosarcoma is a relatively uncommon malignancy however, it is the most common form of primary malignant bone tumors in human. diagnosis and prognosis of patients with osteosarcoma is limited to clinico-radiopathological parameters, whereas molecular markers of tumor aggression have been poorly identified. survivin, an inhibitor of apoptosis (iap), is unique for its expression in human tumors ...