نتایج جستجو برای: آنتی tumor necrosis factor tnf

تعداد نتایج: 1254222  

Journal: :European Journal of Translational and Clinical Medicine 2022

Background: Concentration of tumor necrosis factor alpha (TNF-alpha) might be useful in selecting patients with paroxysmal atrial fibrillation (PAF) who will benefit the most from pulmonary vein isolation.

Journal: :International Journal of Health Sciences (IJHS) 2022

Background: Type 1 diabetes mellitus (T1DM) is a chronic, immune-mediated disease characterized by the destruction of insulin-producing β cells in pancreas. This study investigated influence single nucleotide polymorphisms (SNP) tumor necrosis factor (TNF-α) –308 G/A (rs1800629,) on T1DM patients. Method: The was included 75 patients and 25 healthy subjects. SNP–308 TNF-α gene detected using po...

Journal: :Middle East Journal of Rehabilitation and Health 2021

: Oral lichen planus (OLP) is a relatively common chronic inflammatory disease. The tumor necrosis factor-alpha (TNF-α) considered as major mediator in inflammation reactions. No review articles have been done on evaluating TNF-α levels before and after performing standard treatments of OLP so far. This study aimed to provide complete the association between this cytokine well determining role ...

Journal: :Applied Biological Chemistry 2022

Abstract Vascular inflammation activated by pro-inflammatory cytokines is an inflammatory response that occurs in the early stages of atherosclerosis. Endothelial dysfunction vascular begins with expression cell surface adhesion molecules cytokines. The purpose this study was to evaluate and verify effects isobavachalcone. In study, we investigated isobavachalcone on responses induced tumor nec...

ژورنال: پیاورد سلامت 2010
امیری, محمد مهدی, بویر, محمد علی, جدلی, زهره, رسولی نژاد, مهرناز, روانبخش, مسعود, روحانی, مهدی, صالحی نوده, علیرضا, صراف نژاد, عبدالفتاح, میرشفیعی, سید عباس,

Background and Aim: The present study was designed to compare the cell death, circulating levels of tumor necrosis factor-α and tumor necrosis factor type-I receptor in Iranian patients with sepsis and normal controls. Materials and methods: Twenty-two patients with sepsis were included in this study. After blood collection, the serum circulating levels of TNF- and TNFRI measured with ELISA ki...

ژورنال: پژوهش در پزشکی 2014
حسین‌پور نیازی, سمیه, عزیزی, فریدون, فلاح قهرودی, عارفه, میرمیران, پروین,

Abstract Background: Diet as one of the most important lifestyle factors play an important role in the control and treatment of diabetes and related outcomes. Among dietary factors legumes as a functional food are rich source of nutrients such as vitamins, minerals, fiber, polyphenols and other antioxidants. The aim of this study was to determine the effect of legume intake in therapeutic lifes...

Journal: :anesthesiology and pain medicine 0
parastou aryana anesthesiology research center, shahid beheshti university of medical sciences, tehran, iran samira rajaei immunology department, school of medicine, tehran university of medical sciences, tehran, iran abdolhamid bagheri cardiology department, school of medicine, shahid beheshti university of medical sciences, tehran, iran forouzan karimi immunology department, school of medicine, shahid beheshti university of medical sciences, tehran, iran ali dabbagh anesthesiology research center, shahid beheshti university of medical sciences, tehran, iran; anesthesiology research center, shahid beheshti university of medical sciences, tehran, iran. tel: +98-9121972368; fax: +98-2122074101; email:

results there was no difference found between the two groups with regard to; gender, basic variables, ejection fraction (ef), cbp time and aortic cross-clamp time. the preoperative levels of il-6 and tnf-α were not different; however, their postoperative levels were significantly higher in the placebo group (p value = 0.01 for il-6 and 0.005 for tnf-α). conclusions this study showed that mgso4 ...

آقاعلی نژاد, حمید, نجفی, رویا, پیری, مقصود,

Background and Objective: Breast cancer is a genetic and chronic inflammatory disease with an increasing incidence among Iranian women. Researchers have shown that regular exercise is presumed to have prophylactic effect and adjuvant therapy in inhibition of tumor growth. So the aim of this study was to assess the effect of endurance training on serum TNF-α in breast cancer bearing mice. Materi...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1991
M Lewis L A Tartaglia A Lee G L Bennett G C Rice G H Wong E Y Chen D V Goeddel

Complementary DNA clones encoding two distinct tumor necrosis factor receptors were isolated from a mouse macrophage cDNA library. The cDNA for murine tumor necrosis factor receptor type 1 (mTNF-R1) predicts a mature polypeptide of 425 amino acids that is 64% identical to its human counterpart, whereas the cDNA of murine tumor necrosis factor receptor type 2 (mTNF-R2) predicts a mature protein ...

2006
S J Levine

Tumor necrosis factor alpha (TNF, TNFSF2) is an important multifunctional cytokine that regulates inflammation, host defense, immune responses, and apoptosis. TNF exists as a membrane-bound 26kDa, type II integral membrane protein, and a 17kDa soluble homotrimeric TNF that is generated via proteolytic cleavage by TNF-a converting enzyme (TACE, ADAM17). Both the membrane-bound and soluble forms ...

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