نتایج جستجو برای: آزمون cca

تعداد نتایج: 124481  

Journal: :Asian Pacific journal of cancer prevention : APJCP 2012
Sopit Wongkham Atit Silsirivanit

Difficulties in cholangiocarcinoma (CCA) management are largely due to the lack of specific biomarkers to diagnose CCA patients at an early stage. Most of CCA patients are diagnosed when the tumors have already extensively invaded and/or metastasized, resulting in poor survival. Definite diagnosis for CCA is through a histopathological study of e liver tissues, which is invasive to obtain the s...

2014
Yichao Lu Dean P. Foster

Canonical Correlation Analysis (CCA) is a widely used statistical tool with both well established theory and favorable performance for a wide range of machine learning problems. However, computing CCA for huge datasets can be very slow since it involves implementing QR decomposition or singular value decomposition of huge matrices. In this paper we introduce L-CCA , a iterative algorithm which ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2011
Yuyan Han Sharon Demorrow Pietro Invernizzi Qing Jing Shannon Glaser Anastasia Renzi Fanyin Meng Julie Venter Francesca Bernuzzi Mellanie White Heather Francis Ana Lleo Marco Marzioni Paolo Onori Domenico Alvaro Guido Torzilli Eugenio Gaudio Gianfranco Alpini

Cholangiocarcinoma (CCA) is a devastating biliary cancer. Melatonin is synthesized in the pineal gland and peripheral organs from serotonin by two enzymes, serotonin N-acetyltransferase (AANAT) and acetylserotonin O-methyltransferase (ASMT). Cholangiocytes secrete neuroendocrine factors, including serotonin-regulating CCA growth by autocrine mechanisms. Melatonin exerts its effects by interacti...

Journal: :Journal of Biological Chemistry 2005

2010
Liping Yu Mingqian Feng Heungnam Kim Yen Phung David E. Kleiner Gregory J. Gores Min Qian Xin Wei Wang Mitchell Ho

BACKGROUND Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are the two most common primary liver cancers, yet there have been no significant advances in effective therapeutics. Mesothelin has been reported as a new therapeutic target in various types of cancer. Here, we investigated the expression of mesothelin in liver cancer and its potential role as a novel therapeutic target for...

2015
XIAOJUN ZENG HUALIN TAO

Cholangiocarcinoma (CCA) is a fatal disease that is typically diagnosed late and treated ineffectively. As the morbidity and mortality rates for CCA rise markedly, patietns with CCA currently have a poor prognosis. However, if it were possible to diagnose CCA early while effective treat methods are available, CCA patients would achieve a better quality of life. Therefore, preventing the process...

Journal: :FEMS microbiology letters 1991
T D Joseph S K Bose

To further characterize the chlamydial cytadhesin (CCA), we have examined it for saturability of binding to HeLa cells that were grown as monolayers and in suspension. The CCA exhibited specific cytadherence properties of binding to HeLa cells that appeared to be saturable. The CCA showed a substantial decrease in binding to trypsin-treated HeLa cells in suspension. This finding, together with ...

2003
Rui Zhang Goichiro Hanaoka Junji Shikata Hideki Imai

In a practical system, a message is often encrypted more than once by different encryptions, here called multiple encryption, to enhance its security. Additionally, new features may be achieved by multiple encrypting a message, such as the key-insulated cryptosystems and anonymous channels. Intuitively, a multiple encryption should remain “secure”, whenever there is one component cipher unbreak...

Journal: :Oncology reports 2009
Chun-Nan Yeh See-Tong Pang Ren-Ching Wu Tsung-Wen Chen Yi-Yin Jan Miin-Fu Chen

Cholangiocarcinoma (CCA), a lethal malignancy afflicting many thousands of patients throughout the world, develops through a multi-step progression. We have established an oral thioacetamide-induced model of rat CCA recapitulating the histologic progression of human CCA, especially for mass-forming CCA (MF-CCA). Our previous DNA microarray study showed MUC4 is overexpressed in rat CCA. Herein, ...

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