This study was carried out to determine the effects of γ-aminobutyric acid on the reproductive performance, antioxidative status and biochemical indices of lactating sows. Forty-two lactating sows (Landrace×Large White) were blocked by body weight, parity and backfat and randomly assigned to 6 treatments: 0 (control), 100, 200, 300, 400 and 500 mg γ-aminobutyric acid /kg diet. The average tempe...

Background and objectivesAmino acid neurotransmitters are closely correlated to the neurological function of brain, imbalance amino can lead a variety diseases. Therefore, development simple method detect five (aspartate, glutamate, glycine, taurine, γ-aminobutyric) in brain is urgently needed.

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme key regulator in folate metabolism. Deficiencies in MTHFR result in increased levels of homocysteine, which leads to reduced levels of S-adenosylmethionine (SAM). In the brain, SAM donates methyl groups to catechol-O-methyltransferase (COMT), which is involved in neurotransmitter analysis. Using the MTHFR-deficient mouse model the purpose...