nano silica-h2so4 is an efficient and mild catalysis system for the regeneration of aldehyde from aldoximes. ketoximes are converted to amides by beckmann rearrangement in the presence of nano silica-h2so4. the reactions are carried out in solvent-free conditions under microwave irradiation (600 w) within 50-120 sec in good yields.

In the title compound, C(15)H(13)Cl(2)NOS, the benzene and thio-phene rings make a dihedral angle of 10.8 (1)°. The dimethyl-amino substituent and the α,β-unsaturated carbonyl group are almost coplanar with respect to the aromatic ring, forming dihedral angles of 4.73 (3)° and 5.0 (2)°, respectively. In the crystal structure, mol-ecules are connected into two-dimensional layers by weak C-H⋯Cl h...

Objective(s): In this study a series of novel colchicine-like β-acetamidoketones was designed and synthesized as potential tubulin inhibitorsMaterials and Methods: The cytotoxicity of the novel synthesized β-acetamidoketones was assessed against two cancerous cell lines including MCF-7 (human breast cancer cells) and A549 (adenocarcinomi...

The Strecker-type degradation of phenylalanine in the presence of 2-pentanal and phenolic compounds was studied to investigate possible interactions that either promote or inhibit the formation of Strecker aldehydes in food products. Phenylacetaldehyde formation was promoted by 2-pentenal and also by o- and p-diphenols, but not by m-diphenols. This is consequence of the ability of phenolic comp...

Aromatic carbonyl compounds in combination with B(C(6)F(5))(3) are able to activate H(2) heterolytically. The reactivity of the carbonyl-B(C(6)F(5))(3) adduct is initiated by its thermal dissociation into components. After H(2) addition, aromatic carbonyl compounds convert into aryl-substituted methanes or alcohols.

A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.

Some new b-lactams bearing biologically important morpholine ring have been synthesized by acylation of amino b-lactams in the presence of morpholine-4-carbonyl chloride. These novel β-lactams were prepared under mild reaction conditions without any solvent in short reaction times. Their biological activities have been examined against microbial agents such as Staphylococcus aureus (S. aureus),...

In the crystal structure of the title compound, C(21)H(25)NO(11), the hexopyranosyl ring adopts a chair conformation and the five substituents are in equatorial positions. An intra-molecular hydrogen bond between the amino group and a neighbouring carbonyl group is found. Two carbonyl groups are disordered and were refined using a split model.

Carbonyl rhenium(I) complexes are efficient catalysts for the regioselective isomerization of terminal propargylic alcohols into α,β-unsaturated aldehydes or ketones which can be used as an unprecedented recyclable catalytic system (up to 10 consecutive runs) in the ionic liquid [BMIM][PF(6)].

Some new b-lactams bearing biologically important morpholine ring have been synthesized by acylation of amino b-lactams in the presence of morpholine-4-carbonyl chloride. These novel β-lactams were prepared under mild reaction conditions without any solvent in short reaction times. Their biological activities have been examined against microbial agents such as Staphylococcus aureus (S. aureus),...