Leptospirosis is an acute infectious disease in humans caused by Leptospira sp. This classified as a zoonosis that usually occurs during the flood and commonly transmitted through rat urine. contact with animals or environment have been contaminated Leptospira. There are wide spectrum clinical manifestations of leptospirosis varying from self-limited to severe disease. enters human body conjunc...

La salud cada día está más correlacionada con el vínculo hombre-animal. pandemia actual de COVID-19, al parecer es una zoonosis emergente, que tiene como pendiente precisar su fuente animal primaria. Por lo se debe considerar que, para tener un control integral la misma, debería enfocar no solo en intervención humanos, sino también los animales y medio donde desenvuelven. requiere interacción e...

Leptospirosis is a global zoonosis caused by pathogenic bacteria of the genus Leptospira. The application CRISPR/Cas9 system has facilitated generation mutants and subsequent evaluation phenotypes. Since DNA breaks induced RNA-guided Cas9 nuclease are lethal to Leptospira, different methodologies were implemented overcome this limitation. Initially, CRISPR interference (CRISPRi) was employed cr...

Introduction Brucellosis is a zoonosis caused by gram-negative coccobacillus bacterium of the genus Brucella, which can be transmitted direct contact with animals or their secretions. Is an acute subacute systemic disease that generally starts two to four weeks after inoculation. Its symptoms are nonspecific, but typically presented fever, night sweats, arthralgias asthenia. Although being ende...

INTRODUCTION Simian parvovirus (SPV) causes severe anemia in immunocompromised macaques. The closely related erythrovirus, parvovirus B19, causes anemia in susceptible humans and can be grown in human bone marrow mononuclear cells in vitro. We hypothesized that SPV may infect humans and replicate in human bone marrow mononuclear cells. METHODS Serum samples from handlers of an SPV-seropositiv...

Outbreaks of buffalopox or pox-like infections affecting buffaloes, cows and humans have been recorded in many parts of the world. Since the first outbreak in India, a large number of epidemics have occurred. Unlike in the previous years, generalized forms of the disease are now rare; however, there are severe local forms of the disease affecting the udder and teats, leading to mastitis thereby...