this study was conducted to compare the bio-efficacy of herbal methionine (h-met) relative to dl-methionine (dl-met) on 160 “ross 308” broiler chickens. dl-met and h-met were added to the basal diet in eight experimental treatments with three and four concentrations respectively in starter, grower and finisher period. blood parameters which were measured at 24 and 42 days of age consisted of: s...

introduction: skin resistance is greatly dependent on its collagen amount and nutritional substances such as crude protein that affect the skin collagen can indirectly influence the skin resistance and increase its strength. in this regard, this study aimed to evaluate the effect of in ovo methionine injection on histomorphometry of the skin layers. methods: thirty fertilized eggs of ross 308 b...

an experiment was conducted to evaluate the effect of dietary crude protein and methionine levels on quality and quantity of egg production. fifteen diets formulated with 3 levels of protein (13, 14 and 15%) and 5 levels of methionine (0.25, 0.28, 0.31, 0.34 and 0.37%) and fed to 420 birds in a 3×5 factorial arrangement. each diet was randomly fed to 4 replicates of 7 birds each and fed for 3 p...

During the last few decades, plant protein ingredients such as soya proteins have replaced fishmeal in the diets of aquacultured species. This may affect the requirement and metabolism of methionine as soya contains less methionine compared with fishmeal. To assess whether methionine limitation affects decarboxylated S-adenosylmethionine availability and polyamine status, in the present study, ...

Amino acids modulate mRNA translation through the 70 kDa ribosomal protein S6 kinase (S6K1) and the general control nondepressible 2 protein kinase (GCN2)/eukaryotic initiation factor 2 alpha eIF2 alpha pathways. The aim of the present study was therefore to explore the signaling cascades potentially modulated by methionine availability in quail muscle QM7 myoblasts using media providing all ot...

Methionine is an indispensable amino acid that, when not incorporated into protein, is converted into the methyl donor S-adenosylmethionine as entry into the methionine cycle. Following transmethylation, homocysteine is either remethylated to reform methionine or irreversibly trans-sulfurated to form cysteine. Methionine flux to transmethylation and to protein synthesis are both high in the neo...

Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent. Methionine used for AdoMet synthesis can be replenished via remethylation of homocysteine. Alternatively, homocysteine can be converted to cysteine via the transsulfuration pathway. Aberrations in methionine metabolism are associated with a numbe...

The Panel noted that N-acetyl-L-methionine is deacetylated in animals and humans to Lmethionine. The bioavailability of methionine from N-acetyl-L-methionine is comparable to that from L-methionine used as such as similar mean plasma methionine concentrations were recorded in pigs and in humans after loading with equimolar quantities of each, as L-methionine and Nacetyl-L-methionine were equall...

The nitrogen-sparing effect of methionine, methionine sulphoxide, homocystine, cystine and choline was studied in rats by determining dialy N excretions during 5 d after changing from a high-protein diet to a protein-free diet, L-glutamic acid was used as a negative control. 2. L-, D- and DL-methionine were equally active in sparing N. L-methionine sulphoxide, DL-homocystine and L-cystine were ...