نتایج جستجو برای: zinc metaborate

تعداد نتایج: 73603  

2014
Yunpeng Huang Zhihao Wu Yu Cao Minglin Lang Bingwei Lu Bing Zhou

Tau hyperphosphorylation is thought to underlie tauopathy. Working in a Drosophila tauopathy model expressing a human Tau mutant (hTauR406W, or Tau(∗)), we show that zinc contributes to the development of Tau toxicity through two independent actions: by increasing Tau phosphorylation and, more significantly, by directly binding to Tau. Elimination of zinc binding through amino acid substitution...

Background: Thalassemia constitutes a major public health problem causing a significant burden on children and their families. Zinc deficiency plays an important role in many thalassemia-related complications like growth retardation, hypogonadism and delayed puberty which are frequently noted in adolescent age. Although zinc is supplemented to thalassemic patients visiting Day Care Center, Yang...

Journal: :Gut 1990
H F Goode J Kelleher B E Walker

Patients with liver disease may be at risk of zinc depletion. We measured polymorphonuclear cell, mononuclear cell, plasma, and erythrocyte zinc values, and erythrocyte carbonic anhydrase activity to assess zinc status in 17 patients with non-alcoholic liver disease (primary biliary cirrhosis and chronic active hepatitis) and 13 patients with alcoholic liver disease. The plasma zinc concentrati...

2015
Victoria G. Pederick Bart A. Eijkelkamp Stephanie L. Begg Miranda P. Ween Lauren J. McAllister James C. Paton Christopher A. McDevitt

Pseudomonas aeruginosa is a ubiquitous environmental bacterium and a clinically significant opportunistic human pathogen. Central to the ability of P. aeruginosa to colonise both environmental and host niches is the acquisition of zinc. Here we show that P. aeruginosa PAO1 acquires zinc via an ATP-binding cassette (ABC) permease in which ZnuA is the high affinity, zinc-specific binding protein....

2014
Bao Chen Jianguo Shen Xincheng Zhang Fengshan Pan Xiaoe Yang Ying Feng

The endophytic bacterium, Sphingomonas SaMR12, isolated from Sedum alfredii Hance, appears to increase plant biomass and zinc-extraction from contaminated soil; however, the mechanism by which this occurs is not clear. Here, the ability of SaMR12 to promote zinc extraction and its effects on root morphology and exudation were examined in hydroponics. Zinc treatment increased shoot biomass by 30...

Journal: :The Journal of clinical investigation 1960
R E FREDRICKS K R TANAKA W N VALENTINE

Studies of the biochemistry of zinc have produced results which are widely divergent because of difficulties in methodology. However, techniques have evolved so that general agreement now exists that dithizone methods give reliable and reproducible measurements of zinc in erythrocytes and sera, and that acid extraction of the zinc from these biological materials produces more consistent and acc...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2008
Nic R Bury Mi Ja Chung Armin Sturm Paul A Walker Christer Hogstrand

Intracellular zinc signaling is important in the control of a number of cellular processes. Hormonal factors that regulate cellular zinc influx and initiate zinc signals are poorly understood. The present study investigates the possibility for cross talk between the glucocorticoid and zinc signaling pathways in cultured rainbow trout gill epithelial cells. The rainbow trout metallothionein A (M...

Journal: :The journal of medical investigation : JMI 2011
Nobuko Sarukura Miho Kogirima Shinji Takai Yoshiaki Kitamura Bukasa Kalubi Shigeru Yamamoto Noriaki Takeda

In the present study, we first examined the dietary zinc intake from food groups in 109 healthy Japanese (24-82 years old, 45 male and 64 female) by means of the 72-h recall method. We then used the ratio of apo/holo-activities of angiotensin converting enzyme (ACE ratio) that is a more sensitive index of zinc nutrition than zinc concentration in the serum and examined the correlation between t...

2012
Akiko Ogawa Naoaki Okuda Katsuya Hio Hideyuki Kanematsu Hidekazu Tamauchi

Zinc plating is widely used to protect steels against corrosion. However, the possibility of a high environmental risk for zinc has been recently discussed among advanced countries and more environmentally-friendly substitutes are required urgently. Therefore, monitoring zinc concentration changes on metallic materials such as steel is very important. We chose to measure zinc concentration chan...

Journal: :Physiological reviews 2015
Taiho Kambe Tokuji Tsuji Ayako Hashimoto Naoya Itsumura

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the whole body, tissue, cellular, and subcellular levels by a number of proteins, with zinc transporters being particularly important. In metazoan, two zinc transporter families, Zn transporters (ZnT) and Zrt-,...

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