relative resistance of 43 iranian as well as introduced apple cultivars to blue mold (penicillium expansum) was studied within years 2010-2011. the fruit physicochemical traits were also evaluated as measures of potential resistance to decay. local p. expansum strains were isolated from decayed apple fruits and the most aggressive isolate (5,000 spores ml-1) used as inoculum. fruits were wound-...

Chitosan is biopolymer with promising properties in wound healing. Chronic wounds represent a significant burden to both the patient and the medical system. Among chronic wounds, pressure ulcers are one of the most common types of complex wound. The efficacy and the tolerability of chitosan gel formulation, prepared into the hospital pharmacy, in the treatment of pressure ulcers of moderate sev...

BACKGROUND AND OBJECTIVE: Similar to other wounds, episiotomy could lead to infections and delayed recovery. Since olive oil has antibacterial and wound healing properties, this study aimed to compare the effects of cold compress with gel packs and topical olive oil on the recovery of episiotomy wounds in primigravid women. METHODS: This clinical trial was conducted on 90 primigravid women refe...

There is a high mortality in patients with diabetes and severe pressure ulcers. For example, chronic pressure sores of the heels often lead to limb loss in diabetic patients. A major factor underlying this is reduced neovascularization caused by impaired activity of the transcription factor hypoxia inducible factor-1 alpha (HIF-1α). In diabetes, HIF-1α function is compromised by a high glucose-...

HYPOTHESIS A number of risk factors for incisional hernia have been identified, but the pathogenesis remains unclear. Based on previous findings of smoking as a risk factor for wound complications and recurrence of groin hernia, we studied whether smoking is associated with incisional hernia. DESIGN Cohort study. Clinical follow-up study for incisional hernia 33 to 57 months following laparot...

BACKGROUND AND THE PURPOSE OF THE STUDY Oral mucositis is one of the most common complications of malignancy chemotherapy. As yet, no absolute treatment has been demonstrated to be effective for chemotherapy-induced oral mucositis. This study evaluates the effectiveness of phenytoin mouthwash as a wound healing agent, on the basis of stimulating effects on fibroblast proliferation. MATERIALS ...

The importance of trace elements such as zinc is well recognized in the context of metabolic response to injury and wound healing. There is post-injury lowering of zinc as part of the so-called 'triggered' biochemical response to trauma even if the trauma is of relatively modest severity (Stoner, 1984). In the catabolic phase of metabolic response to trauma, which starts 24-48h post-injury, the...

BACKGROUND Poststernotomy mediastinitis is a rare, but life-threatening complication, thus early diagnosis and proper management is essential for poststernotomy mediastinitis. The main treatment for mediastinitis is aggressive debridement. Several options exist for reconstruction of defects after debridement. The efficacy of immediate debridement and reconstruction with a pectoralis major muscl...

Angiogenesis is required for wound healing and repair, but dysregulated angiogenesis is involved in gastrointestinal inflammation. Bacillus polyfermenticus (B.P.) is a probiotic bacterium clinically used for a variety of intestinal disorders in East Asia. Here we investigated the effect of B.P. on angiogenesis of human intestinal microvascular endothelial cells (HIMECs) and wound healing in int...

Breast cancers that occur in women 2-5 years postpartum are more frequently diagnosed at metastatic stages and correlate with poorer outcomes compared with breast cancers diagnosed in young, premenopausal women. The molecular mechanisms underlying the malignant severity associated with postpartum breast cancers (ppBCs) are unclear but relate to stromal wound-healing events during postpartum inv...