Endophytic microorganisms are recognized as potential source of novel chemical molecules that might be useful in the treatment of infectious diseases. This study was conducted with the aim to isolate and identify endophytic bacteria from medicinal plants recommended for cancer therapy with a potential to produce L-asparaginase. Five different plants were selected to enhance diversity as Cathara...

This study presents a preliminary data of occurrence of elemental concentration in medicinal plants i.e Apium graveolens (seed), Sida cordifolia (root), Solanum surattense (whole plant), Tribulus terrestris(fruit) and Withania somnifera (root) used in Ayurveda, using Atomic absorption spectrometer (AAS) following standard procedures. The elemental concentration i.e. Mn, Na, K, Cl, Ca, Cr, Co, C...

Background: Emergence of bacterial resistance is critically an alarming situation in the health care industries. The medicinal plants have been used in the folk medicine to treat diseases without knowing their active compounds. Objectives: The aim of present study was to screening the antibacterial activities of Withania somnifera leaf extract against antibiotic resistant strains of Staphylococ...

There are varieties of traditional medicinal plants widely used for boosting memory. These include Bacopa monnieri, Rhodiola rosea, Ginkgo biloba, Withania somnifera, etc. Memory effect such is solely attributed to their active phytoconstituents. constituents also referred as smart drugs. capable crossing blood brain barriers. They enhance the cognitive performance in by acting on memory make i...

OBJECTIVE The objective of this paper is to review the literature regarding Withania somnifera (ashwagandha, WS) a commonly used herb in Ayurvedic medicine. Specifically, the literature was reviewed for articles pertaining to chemical properties, therapeutic benefits, and toxicity. DESIGN This review is in a narrative format and consists of all publications relevant to ashwagandha that were i...

The herbicidal activity of Withania somnifera (L.) Dunal against the noxious weed parthenium (Parthenium hysterophorus L.) was evaluated. In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5%, 10%, 15% and 20% w/v concentrations (on a fresh weight basis) of W. somnifera were tested against the germination and seedling growth of parthenium. In gener...

Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides. As genomic information regarding this plant is very limited, little information is available about biosynthesis of withanolides. To facilitate the basic understanding about the withanolide biosynthesis pathways, we performed tr...

Withania somnifera (ashwagandha) is a widely used herb in the Ayurvedic system of medicine. The objective of the present study was to elucidate the effect of W. somnifera root extract (Ws) alone or in combination with exogenous gamma-amino butyric acid (GABA), a GABA receptor agonist or with diazepam, a GABA receptor modulator against pentylenetetrazol (PTZ, iv) seizure threshold in mice. Minim...

Parkinson's disease (PD) is a neurological condition that worsens with age (i.e., 1% of people over 65) no permanent cure. Hence, finding disease-modifying agent fewer undesirable side effects urgently needed. pathology results in the degeneration dopaminergic (DAergic) neurons by accumulating lewy bodies, alpha-synuclein (-syn), lowering anti-oxidants, increasing neuronal inflammation, and alt...