Capacitated p-median problem (CPMP) is a well-known facility-location problem, in which p capacitated facility points are selected to satisfy n demand points in such a way that the total assigned demand to each facility does not exceed its capacity. Minimizing the total sum of distances between each demand point and its nearest facility point is the objective of the problem. Developing an effic...

this paper deals with a multi-period fixed charge production-distribution problem associated with backorder and inventories. the objective is to determine the size of the shipments from each supplier and backorder and inventories at each period, so that the total cost incurred during the entire period towards production, transportation, backorder and inventories is minimised. a 0-1 mixed intege...

Background: Irreversible electroporation (IRE) is a novel tumor ablation technique. IRE is associated with high electrical fields and is often reported in conjunction with thermal damage caused by Joule heating. For good response to surgery it is crucial to produce minimum thermal damage in both tumoral and healthy tissues named Non-Thermal Irreversible Electroporation(NTIRE). Non-thermal irrev...

microgrids are small-scale, low voltage (lv) power networks which employ renewable distribution energy resources (ders) with power electronic interfaces (peis). microgrids as single controlled units and active distribution networks require flexible control systems to ensure reliable and secure operation in different modes. these various operations of microgrid cause variations in voltage and fr...

objective(s): the structure- activity relationship of a series of 36 molecules, showing l-type calcium channel blocking was studied using a qsar (quantitative structure–activity relationship) method. materials and methods: structures were optimized by the semi-empirical am1 quantum-chemical method which was also used to find structure-calcium channel blocking activity trends. several types of d...

scheduling of production in flexible manufacturing systems (fmss) has been extensively investigated over the past years and it continues to attract the interest of both academic researchers and practitioners. the generation of new and modified production schedules is becoming a necessity in today’s complex manufacturing environment. genetic algorithms are used in this paper to obtain an initial...

this paper presents a hybrid approach to developing a short-term traffic flow prediction model. in thisapproach a primary model is synthesized based on neural networks and then the model structure is optimized throughgenetic algorithm. the proposed approach is applied to a rural highway, ghazvin-rasht road in iran. the obtainedresults are acceptable and indicate that the proposed approach can i...

application of cogeneration systems based gas turbine for heat and power production is increasing. because of finite natural energy resources and increasing energy demand the cost effective design of energy systems is essential. cgam problem as a cogeneration system is considered here for analyzing. two new approaches are considered, first in thermodynamic model of gas turbine and cogeneration ...