AIM This study was designed to compare the efficacy and tolerability of bowel preparations with and without the higher first-dose volume of polyethylene glycol (PEG) solution or exercise after drinking PEG solution in Chinese people. METHODS A total of 330 participants who had a colonoscopy done in Peking Union Medical College Hospital were randomly and evenly assigned to three groups. Partic...

The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA on chemical structure, hydrolysis, solubility, hemolysis, cell cytotoxicity in...

Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissolution be...

This protocol describes how to transform moss (Physcomitrella patens) protoplasts using polyethylene glycol (PEG)-mediated DNA uptake. The transformation rates for direct uptake by protoplasts of DNA with and without genomic sequence (a targeting construct) are typically 10 and 10, respectively. (These are the frequencies of stable transformants among regenerants surviving the transformation pr...

The synthesis of clickable polysaccharides was achieved by using alkynylated 1,6-anhydro glucopyranose as a monomer and BF3·OEt2 as an effective catalyst. Subsequent click conjugation with polyethylene glycol (PEG) afforded PEG-grafted polysaccharides in nearly quantitative efficiency.

Physiological response of cotton (Gossypium hirsutum L.) genotype R405-2000 at the youthful stage to water deficit induced by polyethylene glycol The effect of water stress induced by polyethylene glycol (PEG) has been studied on germination and seedling growth of cotton. Five different concentrations of PEG have been tested and the results showed that PEG concentrations negatively influence se...

Two sets of composite membranes having an asymmetric sulfonated polysulfone membrane as support layer have been obtained and electrically characterized (membranes SPS-PEG and PA-LIGS). The skin layer of the membrane SPS-PEG contains different percentages of polyethylene glycol in the casting solution (5, 25, 40, and 60 wt%), while lignosulfonate was used for manufacturing PA-LIGS membranes (5, ...

Cationic waterborne polyurethane as a new dispersing polymer was synthesized by using relatively hydrophilic polyols. Dispersing cationic polyurethane (DCPU) nanocomposites were prepared using isophorone diisocyanate (IPDI), polyethylene glycol (PEG) with different molecular weights (Mn=200, 400, 600,and1000 g/mol), N-methyl diethanolamine (MDEA), dibutyltin dilaurate (DBTDL) and different perc...

The natural populations of East Indian sandalwood (Santalum album L.) are very confined and facing a drastic decline over the past three decades due to overexploitation. Santalum L. seeds, in general, have poor staggered germination, which is major constraint raising seedlings nursery establishing plantations. In present investigation, we studied impact hydro- osmopriming on germination attribu...