OBJECTIVE To assess the performance characteristics of the Institute for Healthcare Improvement Global Trigger Tool (GTT) to determine its reliability for tracking local and national adverse event rates. DATA SOURCES Primary data from 2008 chart reviews. STUDY DESIGN A retrospective study in a stratified random sample of 10 North Carolina hospitals. Hospital-based (internal) and contract re...

Midkine (MK), a heparin-binding growth factor, is overexpressed in a wide range of human carcinomas and is believed to contribute to tumorigenesis and tumor progression. To develop an antitumor reagent, we designed a phosphorothioate antisense oligodeoxynucleotide molecule based on the secondary structure of MK mRNA. The antisense MK at the dosage of 5 microM suppressed MK production by CMT-93 ...

Women’s participation in the labor force has increased substantially over the past half century. In 1930, 10 million women were in the labor force. They represented 24 percent of all working age women and 22 percent of the total work force. By 1955 the number of women workers had doubled, and their labor-force paticipation rate had risen to 36 percent. By 1979 the number had more than quadruple...

BACKGROUND The UK Biobank is a unique resource for biomedical research, with extensive phenotypic and genetic data on half a million adults from the general population. We aimed to examine the effect of neurodevelopmental copy number variants (CNVs) on the cognitive performance of participants. METHODS We used Affymetrix Power Tools and PennCNV-Affy software to analyze Affymetrix microarrays ...

A series of 155 cases of hepatic hydatid disease, occurring in 121 patients, were operated on at the Naval and Veterans Hospital of Athens. Ultrasonography and computerized axial tomography provided the preoperative diagnosis in 89 and 93 percent of the cases respectively in recent years. Thirty one percent of the cases presented with complications, the commonest of these being infection of the...

With increasing mammogram rates, identifying attributes of non-attending women entails going beyond differences in demographic groups to reveal complex interactions among personality attributes. In this study, we analyzed survey data from 474 women aged 41 years and older using decision trees. By incorporating personality, religiousness, and age, we were able to correctly classify 42.9 percent ...

BACKGROUND The aim of this study was to assess the utility of a two-phase case detection strategy for major depressive disorder and a quantitative self-rating instrument for dysphoria. METHODS A convenience sample of 302 ambulatory patients received three self-administered depression rating instruments: a modified version of the Dartmouth Cooperative (COOP) Functional Health Assessment Chart ...

Abstract Two reduced projective schemes are said to be Cremona equivalent if there is a map that maps one in the other. In this paper I revise some of known results about equivalence and extend main result Mella Polastri (Bull Lond Math Soc 41(1):89–93, 2009) [20] reducible schemes. This allows prove very general contractibility for union rational subvarieties.

Midkine (MK), a heparin-binding growth factor, is overexpressed in a wide range of human carcinomas and is believed to contribute to tumorigenesis and tumor progression. To develop an antitumor reagent, we designed a phosphorothioate antisense oligodeoxynucleotide molecule based on the secondary structure of MK mRNA. The antisense MK at the dosage of 5 M suppressed MK production by CMT-93 mouse...

Biolubricants may be obtained from vegetable oils using appropriate chemical modifications, to improve their physicochemical properties for lubrication applications. In this study, the esterification of a free fatty acid (FFA) with long chain alcohols was performed sulfonated mesoporous silica as catalyst. Fresh and functionalized MCM-41 samples were prepared evaluate effect sulfonic surface gr...