Wegener's granulomatosis (WG) has two different clinical phases: the initial phase and generalized phase. In patients with generalized WG, both steroids and cyclophosphamide have generally been used. We report a case of generalized WG that was temporarily, but successfully treated with sulfamethoxazole-trimethoprim (S/T) alone. S/T therapy reduced the elevated levels of soluble IL-2 receptor an...

Among the anti-neutrophil cytoplasmic antibodies (ANCA), those targeting proteinase 3 (PR3) have a high specificity for Wegener's granulomatosis (WG). It is known that a preceding priming of neutrophils with cytokines is a prerequisite for membrane surface expression of PR3, which is then accessible to autoantibody binding. Employing a monoclonal antibody directed against human PR3 and ANCA-pos...

Abstract We propose and numerically investigate integrated photonic crystal waveguides (PhC-WGs) formed in a semiconductor slab to realize an ultrasmall highly efficient terahertz (THz) wave source. The structure consists of straight PhC-WG with low-group-velocity low-dispersion (LVLD) for difference frequency generation (DFG) connected two PhC-WGs introduce fundamental lights into the LVLD PhC...

BACKGROUND Current findings on associations between whole grain (WG) intake and mortality are inconsistent and have not been summarized by meta-analysis. METHODS AND RESULTS We searched for prospective cohort studies reporting associations between WG intake and mortality from all causes, cardiovascular disease (CVD), and cancer through February 2016 in Medline, Embase, and clinicaltrials.gov,...

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An obvious problem in this area is payload inspection of encrypted traffic: since the network-based intrusion detection system (NIDS) commonly has no access to the encryption keys, it can not decrypt the captured data and, therefore, no analysis is possible. From a network perspective it is thus hard to deal with encrypted traffic. However, more and more traffic within networks uses some form o...

Wegener's granulomatosis (WG) is a systemic vasculitis of small- to medium-sized arteries, associated with necrotizing granulomata classically involving the upper and lower respiratory tracts and kidneys. It is usually associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). ANCA-negative WG is usually a limited form of the disease that tends to affect organs other than th...

Remark. If G is a compact Lie group with maximal torus TG and Weyl Group WG, the finitely generated free Z-module LG = π1TG has a natural action of WG and is called the dual weight lattice of G. The group G is simple in the usual sense if and only if the center of G is trivial and the action of WG on Q ⊗ LG gives an irreducible representation of WG over Q. From this point of view 1.3 is a direc...