"PRECISE determination of the optimal allocation of resources within the health service, and between the health service and other wants of society, may be impossible. But to think in terms of optimal allocation, instead of 'meeting needs,' will produce better decisions." This is a quotation fronm a critical review (Feldstein, 1963) of the recent Nuffield study of operational research in the hea...

the clinical and economic importance of heart failure is widely recognized.   the incidence of heart failure is on the increase, particularly with the aging of the population around the world.   it is time for a paradigm shift in heart failure management. alternative non-pharmacological strategies to remodel the failing ventricle will shape a major portion of heart failure therapy in the decade...