Lack of cytocompatibility in bone substitutes impairs healing in surrounding bone. Adverse biological events around biomaterials may be associated with oxidative stress. We hypothesized that a clinically used inorganic bone substitute is cytotoxic to osteoblasts due to oxidative stress and that N-acetyl cysteine (NAC), an antioxidant amino acid derivative, would detoxify such material. Only 20%...

Many applications in machine learning, natural language processing, and information retrieval require methods for representing and computing with text documents. In this review, we discuss techniques that use latent, topical information in text documents for solving problems in these fields. We consider approaches to problems such as document retrieval, topic tracking, novel event detection, do...

This study was conducted to evaluate the increase of DPPH radical scavenging activity of meat substitute by heating. The meat substitute showed higher DPPH radical scavenging activity than those of other foods rich in protein such as beef, pork, chicken, and soybean curd. The DPPH radical scavenging activity of meat substitute was dependent upon concentration, heating temperature and heating ti...

Operator splitting methods are often used to solve convection-diiusion problems of convection dominated nature. However, it is well known that such methods can produce signiicant (splitting) errors in regions containing self sharpening fronts. To amend this shortcoming, corrected operator splitting methods have been developed. These approaches use the wave structure from the convection step to ...

MOTIVATION Genomic and proteomic approaches have accumulated a huge amount of data which provide clues to protein function. However, interpreting single omic data for predicting uncharacterized protein functions has been a challenging task, because the data contain a lot of false positives. To overcome this problem, methods for integrating data from various omic approaches are needed for more a...

The functioning of fuel cells, in which simultaneous processes having different kinetics and different time constants occur, can be simulated by applying rather complex models. For the sake of better modeling larger numbers of sub-processes and their couplings have to be considered, which leads to complex and multi-step simulation frameworks. In this work new methods are introduced for the simu...