Zinc supplementation reduces the duration, severity and recurrence of diarrhoea in young children. This study examines whether zinc, found naturally in drinking water, reduced infant deaths from diarrhoea in rural Bangladesh. Information was compiled for births over two calendar years with follow-up for deaths within one year of birth. The study included 29,744 live births and 934 deaths in som...

During the perinatal period, a dramatic reversal of lung transepithelial ion and water transport occurs that involves the amiloride-inhibitable Na+ channel (ENaC). Aquaporin (AQP) water channel proteins facilitate cell membrane water transport. We now report that AQP-4, localized to basolateral membranes of airway epithelial cells, increases its mRNA expression in developing lung eightfold duri...

BACKGROUND In developing countries, maternal and neonatal mortality is high. Among the causes of death during the neonatal period, low birth weight is crucial. A dose of fluoride beyond 2mg/L causes enamel damage, possibly affecting the fetus. The aim of this study was to search for an association between dental fluorosis in the mother and low birthweight of the newborn. METHODOLOGY This was ...

In 2014, the city of Flint, MI, in USA changed its public water source, resulting severe contamination and a health crisis. Using Flint crisis as natural experiment, we estimate effect utero exposure to polluted on at birth. Matching vital statistics birth records with various sources data, use synthetic control method identify causal impact pollution key outcomes. Our results suggest that mode...

background: feeding intolerance is a common problem among premature infants. there is limited information on the safety and effects of oral probiotic supplements, especially products containing lactobacillus reuteri, and the incidence of necrotizing enterocolitis (nec) in low birth weight preterm infants. this study aimed to evaluate the effects of lactobacillus reuteri on the gastrointestinal ...

BACKGROUND Hypospadias is a relatively common birth defect affecting the male urinary tract. It has been suggested that exposure to endocrine disrupting chemicals might increase the risk of hypospadias by interrupting normal urethral development. METHODS Using data from the National Birth Defects Prevention Study, a population-based case-control study, we considered the role of maternal expos...