It has been reported that mumps virus protein V or the C-terminal Cys-rich region of protein V (Vsp) is associated with blocking of the interferon (IFN) signal transduction pathway through a decrease in STAT-1 production. The intracellular target of the V protein was investigated by using a two-hybrid screening system with Vsp as bait. Full-length V protein and Vsp were able to bind to RACK1, a...

Reliable, accurate and noninvasive methods for measuring lung function in infants are desirable. Electromagnetic inductance plethysmography has been used to perform infant spirometry and VoluSense Pediatrics (VSP) (VoluSense, Bergen, Norway) represents an updated version of this technique. We aimed to examine its accuracy compared to a validated system measuring airflow via a facemask using an ...

BACKGROUND Neurological involvement is common in the spirochetal infection relapsing fever (RF) in both humans and experimental animals. RF is best known for antigenic variation caused by the sequential expression of variable outer membrane lipoproteins of 2 sizes, variable small (Vsp) and variable large (Vlp) proteins. Less understood is the persistence of RF borreliae in the brain after they ...

DNA mismatch repair (MMR) and very-short patch (VSP) repair are two pathways involved in the repair of T:G mismatches. To learn about competition and cooperation between these two repair pathways, we analyzed the physical and functional interaction between MutL and Vsr using biophysical and biochemical methods. Analytical ultracentrifugation reveals a nucleotide-dependent interaction between Vs...

The vehicle scheduling problem (VSP) is a problem of interest to many researchers and practitioners. The general VSP is concerned with minimizing the total distance associated with a fixed set of vehicle routes by determining which vehicles will satisfy the demands at various customer locations. The design of most general distribution systems usually involves the assignment of permanent custome...

Unknown remaining time of signal phase at a signalized intersection generally results in extra accelerations and decelerations that increase variations of operating conditions and thus emissions. A cooperative vehicle-infrastructure system can reduce unnecessary speed changes by establishing communications between vehicles and the signal infrastructure. However, the environmental benefits large...

The list of indications for which Variable Square Pulse (VSP) Er:YAG laser systems can be used is continuously expanding. For example, ablative fractional resurfacing treatments performed with the VSP Er:YAG laser have good clinical outcomes and significantly shorter recovery times and adverse effects compared with traditional ablative laser skin resurfacing. Recently, an Er:YAG laser operating...

The conceptual aircraft designer is faced with a dilemma, how to strike the best balance between productivity and fidelity? Historically, handbook methods have required only the coarsest of geometric parameterizations in order to perform analysis. Increasingly, there has been a drive to upgrade analysis methods, but these require considerably more precise and detailed geometry. Attempts have be...

The abundance of all tetra- and pentanucleotide sequences is calculated for a set of DNA sequence data comprising 767,393 nucleotides of the E. coli K-12 genome. Observed frequencies are compared to those expected from a Markov chain prediction algorithm. Systematic and extreme non-random representations are found for special sets of sequences. These are interpreted as arising from incorporatio...

Seismic reflection can provide precise estimates of subsurface structures. To obtain more information on subsurfaces using the same amount data, we first compared reverse time migration (RTM) images obtained from surface seismic profile (SSP), vertical (VSP), and single well (SWP) data for models that included faults with various dips. When were sufficient, SSP, SWP, VSP surveys suitable identi...