The reactivity of lymphoid cells from germfree and conventional CDF rats were compared in mixed leukocyte culture (MLC) with both allogeneic rat leukocytes and with human leukocytes as stimulating cells, and in a graft-versus-host (GVH) assay. There was no difference between germfree and conventional rats in any of these systems. Furthermore, the increase in GVH activity after specific immuniza...

The immunorestorative effect of Cimetidine in vitro on the T cell-induced local GVH reaction in vivo was studied in 43 cancer patients and 43 normal healthy donors. Both low dose (10(-5) M) and high dose (10(-4) M) Cimetidine induced significant, albeit partial, immune restoration among GVHR-negative cancer patients (p less than 0.05, p less than 0.01, respectively) with the high dose being sig...

Autoimmune thyroid diseases (AITD) show a female predominance, with an increased incidence in the years following parturition. Fetal microchimerism has been suggested to play a role in the pathogenesis of AITD. However, only the presence of fetal microchimeric cells in blood and in the thyroid gland of these patients has been proven, but not an actual active role in AITD. Is fetal microchimeris...

The graft versus host (GVH) reactivity of Lewis (L) rat spleen cells was measured using a popliteal lymph node (PLN) assay in Lewis-Brown Norway (LBN) recipient rats. Specific sensitization of donors with a single intravenous injection of LBN spleen cells 7-14 days prior to assay resulted in a significant decrease in GVH reactivity. Thirdparty sensitization of donors with Lewis-Buffalo spleen c...

Vol. XXXVII (August 2000), 331–350 331 *Chris Janiszewski is Jack Faricy Associate Professor of Marketing, University of Florida (e-mail: [email protected]). Stijn M.J. van Osselaer is Assistant Professor of Marketing, University of Chicago (email: [email protected]). Both authors contributed equally to this article. This work was supported by the Beatrice Foods Co. Fa...

There are two moral ethical dichotomies in healthcare: consequentialism versus deontology and individualism versus collectivism. When the physician is faced with the dilemma of deciding between one versus many, he often has to resort to the principle of promoting the greatest good for the greatest number, or the principle of maximizing utility. Utilitarianianism is the creed which accepts as th...

Three studies explored how the traits that people ideally desire in a romantic partner, or ideal partner preferences, intersect with the process of romantic relationship initiation and maintenance. Two attraction experiments in the laboratory found that, when participants evaluated a potential romantic partner’s written profile, they expressed more romantic interest in a partner whose traits we...