The renewed interest in medicinal plants has led us to examine more closely the usefulness of metabolite histolocalisation screening work before any in-depth phytochemical studies. Indeed, this method is a histochemical technique allowing characterizing plant tissues constituents; and particular metabolites therapeutic interest, without destroying or altering as much possible studied material. ...

Background: For many women, the monthly suffering induced by menstrual “cramps” is severe enough to profoundly disrupt their quality of life. In the case of primary dysmenorrhea, a condition related to premenstrual syndrome (PMS), intense uterine contractions are thought to trigger moderate to intense pain despite the absence of an underlying infection or other medically-identifiable disease st...

Objectives: 1) to determine the elasticity of normal breast tissue (parenchyma and premammary adipose tissue) in healthy women using ultrasound two-dimensional shear wave elastography (2D-SWE); 2) reveal a possible correlation between increased stiffness parenchyma hyperprolactinemia patients with mastodynia mastopathy; 3) evaluate ability Vitex agnus-castus drug reduce glandular tissue; 4) obj...

The effectiveness for vasomotor symptoms and sleep disorders plus the long-term safety of a nutraceutical combination of agnus-castus and magnolia extracts combined with soy isoflavones (SI) and lactobacilli were assessed in postmenopausal women. A controlled study was carried out in menopausal women comparing this nutraceutical combination (ESP group) with a formulation containing isoflavones ...

The aim of the present study was to evaluate the effect of a hydro-alcoholic extract of Vitex agnus-castus (VAC) fruit on blood urea nitrogen (BUN), creatinine (Cr) and, kidney histology of a female mouse model of D-galactose induced aging. In this experimental study, 72 NMRI mice were divided into 6 groups: control, VAC, D-galactose, D-galactose+VAC, aging, and aging+VAC. D-galactose was injec...

Gallic acid (GA) is the main phenolic antioxidant which has been subjected of many studies because of its important biological properties including anticancer, anti-inflammatory and antimicrobial activities as well as free radicals scavenger and cardiovascular diseases protector. Hereupon, fabricating a selective and sensitive sensor for GA detection and measurement is an important issue. In th...