Passados 12 meses do início da pandemia causada pelo novo coronavírus o número de contaminados e mortos continua aumentando vertiginosamente. Mesmo as autoridades não prestando informações relacionando-as a quesitos étnicos-raciais, diversas pesquisas estudos dão conta que população negra é mais atingida fatalmente pela doença. A proposta deste artigo analisar questões estruturais fazem com sej...

viral protein-1 (vp1) is a major capsid protein of coxsakievirus b3 (cvb3) that plays an important role in directing viruses towards permissive cells and acts as a main antigenic site of the virus in eliciting of host immune response, hence it seems vp1 can be considered as a vaccine candidate against cvb3 infection. in this study, cdna of vp1 was prepared, cloned into pet expression vector and...

objective(s): first, 10-bromodecanoic acid was covalently attached to all available surface primary amines of ppi g2 and g3 to increase their lipophilicity. in the subsequent step, ppis were conjugated to the alkylcarboxylate groups of alkylcarboxylate-ppi derivatives to increase the number of surface primary amines. physicochemical properties of modified ppis were determined. transfection expe...

human parvovirus b19, the causative agent of fifth disease in childhood, is non-enveloped dna virus and resistant to many physicochemical agents. b19 is a potential risk to hemophiliac patients receiving blood products. to determine the prevalence of the corresponding antibody in patients with hemophilia a or b or von will brand’s disease (vwbd), we tested 180 hemophilia patients aged 1-45 year...

background viral hepatitis is a systemic infection affecting the liver predominantly. almost all cases of acute viral hepatitis are caused by one of five viral agents: hav, hbv, hcv, hdv and hev. the present study aimed to find out the frequency of various forms of viral hepatitis (hav, hbv, and hcv), route of transmission, the history of vaccination against hepatitis b, and clinical findings i...

Background: Viral load and alanine aminotransferase (ALT) levels may not be the key points for making a decision in the treatment of anti-HBe positive chronic hepatitis B. The purpose of this study was to assess the histological evaluation of liver to find the need for treatment on 72 patients with anti-HBe positive chronic hepatitis B. Methods: The liver biopsy slides of the 72 patients (56 s...

Un nuevo coronavirus zoonótico, declarado como pandemia y nombrado 2019 betacoronavirus novel (2019-nCoV o COVID-19) por la Organización Mundial de Salud, ha sido identificado el agente causante epidemia neumonía viral originada en Wuhan, China, a finales del 2019. Su amplia propagación se debe gran medida las características patogénicas que permitenuna transmisibilidad eficiente persona median...

An in vitro study was conducted to know the veridical properties of silver nanoparticles synthesized from   locally available white button mushrooms (Agaricus bisporus). The characterized colloidal silver nanoparticles exhibited as an excellent virucidal property on viral strain Bacteriophage. The viral inactivation process was increased with increasing the concentration of colloidal s...