The problem arises in vanamei shrimp cultivation is the emergence of diseases, such as vibriosis caused by Vibrio parahaemolyticus. Jatropha leaf extract can be used an immunostimulant because it contains bioactive compounds namely flavonoid, tannins, saponins, and alkaloids. This research a completely randomized design (CRD) with 5 treatments 3 replications. were; P1 (feed without bacterial in...