نتایج جستجو برای: vesicle trafficking

تعداد نتایج: 68740  

Journal: :Genes 2023

We report a 49-year-old patient suffering from spastic paraplegia with novel heterozygous mutation and analyzed the levels of heat shock proteins (hsp)-27, dopamine (DA), its metabolites in their cerebrospinal fluid (CSF). The hsp27 protein concentration patient’s CSF was assayed by an ELISA kit, while DA CSF, 3,4-dihydroxyphenylacetic acid (DOPAC), Cys-DA, Cys-DOPA were measured HPLC. Whole ex...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2014
Paulo S Pinheiro Anna M Jansen Heidi de Wit Bassam Tawfik Kenneth L Madsen Matthijs Verhage Ulrik Gether Jakob B Sørensen

Protein Interacting with C Kinase 1 (PICK1) is a Bin/Amphiphysin/Rvs (BAR) domain protein involved in AMPA receptor trafficking. Here, we identify a selective role for PICK1 in the biogenesis of large, dense core vesicles (LDCVs) in mouse chromaffin cells. PICK1 colocalized with syntaxin-6, a marker for immature granules. In chromaffin cells isolated from a PICK1 knockout (KO) mouse the amount ...

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