I n May 2007, a 62-year-old man presented with a 6-cm fungating mass on the dorsum of the tongue (Figure 1), which had lasted for an unknown period of time. The lesion had a roughened and irregular surface, with areas of white keratosis admixed with areas of necrosis. It felt indurated on palpation. Two additional smaller exophytic lesions were observed on the dorsum of the tongue: one adjacent...

Verrucous carcinoma of the vulva is a rare lesion (1). Affecting essentially postmenopausal women, this lesion is a distinct and particular entity in vulval carcinoma classification and its scalability is uncertain and unpredictable. Here, we present a case concerning a 48-year-old patient, without follow-up after a condyloma acuminate of the vulva (large left lip). The origin of this case will...

We present a case of verrucous carcinoma of the foot in a 34-year-old man. This is a rare, locally invasive, well-differentiated, low-grade squamous cell carcinoma, with human papilloma virus as a possible causative agent. It follows a chronic course and mimics a variety of skin lesions, delaying diagnosis by up to 15 years. The definitive diagnosis is made histologically, and treatment by wide...

Penile verrucous carcinoma also known as Buschke-Löwenstein tumor in the genital region is an uncommon variant of penile carcinoma exhibiting slow, expansive growth. We present a case of a 63-year-old male who presented with a giant purulent penile mass causing urinary sepsis and angina. Regional lymph nodes were clinically negative and staging with CT scans of thorax and abdomen did not show a...

We report a case of rapid progression of carcinoma of the penis, in a 90-year-old man, one year after yttrium-aluminum-garnet (YAG) laser therapy. This patient had received YAG laser ablation for well-differentiated, verrucous, squamous cell carcinoma of the penis at the age of 89, and was found on physical examination to have local recurrence. The recurrent tumors were surgically resected, and...

Squamous cell carcinoma (SCC) is the most prevalent malignant neoplasm of the oral cavity. The conventional tumour and several histologic subtypes of SCC present morphologic features and specific behaviour when they occur in the oral mucosa. For example, basaloid SCC is an aggressive tumour and verrucous carcinoma has the lowest invasive and metastatic potential; however, the clinical and biolo...

carcinoma. Lesions from a case in which papovavirus was evident were transmitted to a healthy person, the virus being found in cell nuclei in the wart lesions and also in lesions with some signs of atypia. This fulfilled the condition for recognition of the virus, demonstrated by electron microscopy, as being causatively involved in the verrucous lesions in epidermodysplasia verruciformis and a...