Objective: Inflammation along with oxidative stress has an important role in the pathophysiology of unstable angina which leads to acute myocardial infarction, arrhythmias and eventually heart failure. Curcumin has anti-inflammatory and anti-oxidant effects and thereby, it may reduce cardiovascular complications. This randomized controlled trial aimed to investigate the effects of curcumin on t...

background pulmonary artery hypertension is the presentation of various types of cardiovascular and systematic diseases. there are different kinds of noninvasive methods to determine right ventricular function, pulmonary artery pressure, and effect of pulmonary hypertension on right ventricular function. these methods include the tissue doppler imaging (tdi) of the tricuspid annulus and the lon...

BACKGROUND Tachycardia-induced cardiomyopathy caused by ventricular tachycardia is a well-defined clinical entity. Less well appreciated is whether simple ventricular ectopy can result in cardiomyopathy. We sought to examine a potential causal relationship between repetitive monomorphic ventricular ectopy originating from the right ventricular outflow tract and cardiomyopathy and the role of ab...

Echocardiography was used to compare the left ventricular function of 43 female patients with stable systemic lupus erythematosus with 93 healthy females in 3 age groups. Left ventricular systolic function was evaluated by the left ventricular ejection fraction and left ventricular diastolic function was evaluated by the diastolic descent rate of the anterior mitral leaflet (DDR), the ratio of ...

As emphasized by Watkins et al.,9 the variability in plasma renin activity in CHF is explained by the degree of compensation in maintaining arterial pressure and plasma volume; the latter measurement was not obtained in the Curtiss or Gavras study. The observations in these two recent studies reaffirm the importance of the RAA system in maintaining systemic vascular resistance (SVR) in CHF. Cur...

The effects of exercise and beta adrenoceptor blockade on left ventricular function were assessed in eight patients with hypothyroidism before and during thyroxine replacement treatment. Left ventricular ejection fraction, measured by radionuclide ventriculography, was reduced in hypothyroid patients at rest and on exercise. The rise in ejection fraction with exercise was, however, similar in b...

the cardiac action of phenoxybenzamine (dibenzyline) was studiedusing the maximum rate of pressure rise in the left ventricle as a measure of myocardial contractility. cardiac function was assessed by increasing the pressure load on the heart and measuring contractility as reflected by dp/dt. dibenzyline was found to change the cardiac response to pressure load. the rate of pressure increase in...

Background. Prior studies in experimental canine models have demonstrated that intravenous cocaine administration causes myocardial depression. The purpose of the present study was to establish the mechanisms of cocaine's actions on myocardial and left ventricular performance after single intravenous bolus doses in conscious, chronically instrumented dogs, in which the full autonomic influences...