introduction: dentin dysplasia is a rare autosomal dominant inheriting disturbance of dentin formation characterized by normal enamel formation, but atypical dentin with abnormal pulpal morphology. there are two major patterns: type i and type ii. amelogenesis imperfecta is an autosomal dominant. x-link inherent disease that is classified by clinical manifestation into hypoplastic, hypomature, ...

Angiogenesis is an important factor in the development of epithelial neoplasias and is useful in the study of progression and metastasis. Neoplastic cells produce angiogenic factors that overtake the antiangiogenic capacity of autoimmune cells. The vascular endothelial growth factor (VEGF) is the most important factor in the neoplastic angiogenesis. In colo-rectal carcinoma the expression of VE...

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia and severe, recurrent epistaxis is a common clinical phenotype associated with HHT. An intranasal treatment regime of diluted AvastinTM (Bevacizumab; recombinant humanized anti-vascular epithelial growth factor immunoglobin G1) using a pulsatile nasal irrigator has proven efficacious in clinical practice. Ho...

K-ras is essential for embryogenesis and its mutations are involved in human developmental syndromes and cancer. To determine the consequences of K-ras activation in urothelium, we used uroplakin-II (UPK II) promoter driven Cre recombinase mice and generated mice with mutated KrasG12D allele in the urothelium (UPK II-Cre;LSL-K-rasG12D). The UPK II-Cre;LSL-K-rasG12D mice died neonatally due to l...

objective: to evaluate the predictive value of some biochemical markers in the outcome of extremity vascular trauma. methods: this study comprised 30 patients with traumatic arterial injury and acute limb ischemia referred to namazi hospital affiliated with shiraz university of medical ssciences, over a period of 8 months, from sep 2009 to jul 2010. venous blood samples were drawn from distal i...

................................................................................................................... 8 Introduction .............................................................................................................. 9 Review of the literature ............................................................................................. 10 1. Normal lung development .......

Placental mesenchymal dysplasia (PMD) is a rare benign placental abnormality. It is characterized by hydropic degeneration of stem villi, placentomegaly, and increased maternal serum alpha-fetoprotein(AFP). It can be associated with different congenital abnormalities, karyotype abnormalities, and feto-maternal morbidities. It is difficult to differentiate PMDfrom partial mole, complete mole wit...

NOT UNCO MMONLY, the need arises for renal arterial surgical procedures but under conditions which would make the use of ordinary vascular reconstructive techniques difficult or impossible, as for example with distally located fibromuscular dysplasia or hilar aneurysm. This study was undertaken to descri be a method of renal au totransplantation by which a kidney can be removed, cooled, perfuse...

Background: Although the imbalance of cytokines in Head and Neck Squamous Cell Carcinoma (HNSCC) is well known, there is scarce data regarding its occurrence during dysplasia, before the malignant transformation. Objective: To determine whether laryngeal dysplasia patients show a different cytokine profile than patients with cancer and healthy controls. Methods: Seventeen newly diagnosed, untre...