Patients with hemophilia are at risk for the development of acquired immunodeficiency syndrome (AIDS). Patients with AIDS have recurrent infections and/or malignancy and altered immune response, including decreased T lymphocyte counts, decreased T helper lymphocytes, defective T cell blastogenesis, hypergammaglobulinemia, defective natural killer (NK) activity and impaired response of NK to int...

Simulations were carried out using penalty finite element analysis with bi-quadratic elements to investigate the influence of uniform and non-uniform heating of bottom wall within a trapezoidal enclosure of various inclination angles ðuÞ. Parametric study has been carried out for a wide range of Rayleigh number ðRaÞ ð10 6 Ra 6 10Þ, Prandtl number ðPrÞ ð0:026 6 Pr 6 988:24Þ and Darcy number ðDaÞ...

Background: Substances with endocrine disrupting properties are under special consideration in European Union regulations. In 2014 the European Commission published a roadmap which presented four possible options for identifying endocrine disruptors (ED). A further option was proposed by the chemical and crop protection industry. Methods: This case study investigated how natural substances (gen...

Natural killer (NK) cells are innate immune lymphocytes that function mainly as immune sentinels against viral infection and tumorigenesis. NK cell function is governed by inhibitory and activating signals arising from corresponding receptors. A prominent group of activating NK receptors is the natural cytotoxicity receptors (NCRs), which includes NKp30, NKp44, and NKp46. These receptors bind v...

OBJECTIVE Nowadays, the occurrence of brown tumor lesions or osteitis fibrosa cystica caused by long-lasting primary hyperparathyroidism are very rare, since measuring serum calcium became available routinely in the mid-1970s. It is a tumor-like lesion that may affect the entire skeleton, often presenting with diffuse focal bone pain or by pathological fracture. METHODS We describe our experi...

the purpose of this paper is to investigate the egm method and the behavior of a solid particle suspended in a twodimensional rectangular cavity due to conjugate natural convection. a thermal lattice boltzmann bgk model is implemented to simulate the two dimensional natural convection and the particle phase was modeled using the lagrangian–lagrangian approach where the solid particles are treat...

Both synthetic and natural estrogens have been studied for their ability to induce renal carcinomas in castrated male hamsters after 9.0 months of treatment. Tumor foci were detected in frozen serial sections stained histochemically for estrase activity. Both diethylstilbestrol (DES) and 17 beta-estradiol had equal ability (100%) to induce renal tumors [approximately 20.5 +/- 3 (S.E.) tumor foc...