Different species have been used to reproduce myocardial infarction models but in the last years mice became the animals of choice for the analysis of several diseases, due to their short life cycle and the possibility of genetic manipulation. Many techniques are currently used for cardiovascular imaging in mice, including X-ray computed tomography (CT), high-resolution ultrasound, magnetic res...

High-resolution X-ray observations of the face-on galaxy M 83 with the HRI onboard ROSAT are presented. The analysis aimed at studying the X-ray point source population inside the galaxy and disentangling the X-ray emission components (i.e. point sources, extended emission from hot gas in the bulge, disk and halo). Within the D25 ellipse of M 83, 21 X-ray sources are detected with (0.1–2.4 keV ...

Low inherent contrast in soft tissues has been limiting the use of X-ray absorption micro-computed tomography (micro-CT) to access high-resolution structural information of animal organs. The staining agents used in micro-CT to improve the contrast fail in providing high-quality images of whole organs of animals due to diffusion problems of the staining agent into the sample. We demonstrate a s...

The purpose is to review in a 4-part series: (i) the basic principles of x-ray production, (ii) x-ray interactions and data capture/conversion, (iii) acquisition/creation of the CT image, and (iv) operational details of a modern multislice CT scanner integrated with a PET scanner. In part 1, the production and characteristics of x-rays were reviewed. In this article, the principles of x-ray int...

High-resolution computed tomography (CT) imaging of a live animal within a lead-lined synchrotron light hutch presents several unique challenges. In order to confirm that the animal is under a stable plane of anaesthesia, several physiological parameters (e.g. heart rate, arterial oxygen saturation, core body temperature and respiratory rate) must be remotely monitored from outside the imaging ...

There is an increasing interest in iterative reconstruction (IR) as a key tool to improve quality and increase applicability of x-ray CT imaging. IR has the ability to significantly reduce patient dose; it provides the flexibility to reconstruct images from arbitrary x-ray system geometries and allows one to include detailed models of photon transport and detection physics to accurately correct...

This research program centers around a two-spectrometer x-ray diffuse-scattering system based on a Rigaku 12-kW rotating-anode x-ray generator. The apparatus is designed in such a way that one may easily tailor the instrumental resolution function to optimize studies of structure and fluctuations in a vast range of physical systems. Angular resolution of 1.8 seconds of arc and sample temperatur...

OBJECTIVE To compare the results of X-ray and CT scan for dysbaric osteonecrosis in Chinese divers. METHODS Both shoulders, hips and knees of 66 asymptomatic divers with diving duration of more than one year were examined by X-ray and CT scan. RESULTS The most frequent locations of dysbaric osteonecrosis were the upper femurs, followed by the upper humerus, lower femurs and upper tibias, an...

Purpose: Compton spectroscopy is a widely accepted tool for measuring the primary X-ray spectra of a diagnostic computed tomography (CT) system. The aim of this work is to spectroscopically detect CT X-ray photons subjected to 90-degree Compton scattering for accurate modelling of CT beam-shaping filtration, which necessary for computation of radiation exposure and for other research applicatio...