AIM To compare the clinical and microbiological results between patients with infectious vaginitis receiving vaginal irrigation with saline or no irrigation before standard antibiotic therapy. METHODS Women with vaginitis (n = 109) were randomized to receive vaginal irrigation with saline or no irrigation before standard antibiotic therapy. The vaginal symptoms perceived by subjects and clini...

OBJECTIVE Although it is FDA-approved for use in vulvovaginal candidiasis caused by non-Candida albicans species, terconazole cream has not been been studied in patients with these infections. We sought to assess the clinical and mycological efficacy of terconazole cream in women with non-C. albicans vaginitis. METHODS The records of patients who had received a 7-day course of terconazole cre...

BACKGROUND/AIMS Intravaginal pentamycin is a polyene macrolide with a broad spectrum of antimicrobial activity and is effective in various forms of infectious vaginitis. We evaluated the safety, tolerability and pharmacokinetics of escalating doses of this product. METHODS Nineteen healthy volunteers were randomized to receive double blind one of five doses of intravaginal pentamycin (3, 10, ...

Although vaginitis caused by Saccharomyces cerevisiae is extremely rare, in recent years we have experienced an increasing frequency of S. cerevisiae isolation from the vaginas of fertile-age women. In order to investigate the epidemiology of these vaginal infections, a total of 40 isolates of S. cerevisiae derived from symptomatic and asymptomatic women were characterized by two DNA typing app...

In Africa many plants are used as antifungals. However, journals analysing the work of antifungal activities in West recent years rare. This study is a synthesis publications from 2006 to 2021 on traditionally fight against diseases. A systematic search was carried out Pub Med and Google Scholar database using following keywords: vaginitis; Africa; activity; medicinal plants; plant extracts; fo...

An open clinical trial was conducted with V-Gel on 31 patients with vaginitis in the age group of 24-62 years. After initial screening of symptomatology and aetiological organisms the patients were enrolled in the trial. All the patients were advised to apply V-Gel twice daily for a period of 2 weeks. A weekly follow-up was done in all the patients to assess the clinical response and side effec...

Haemophilus somnus was consistently isolated from vaginal discharges of dairy cows submitted from field cases of vaginitis, cervicitis and/or metritis in the KwaZulu-Natal Midlands during the period July 1995 - December 2000 and from the East Griqualand area in November/December 2000. The purulent vaginal discharges, red granular vaginitis and cervicitis, and pain on palpation described in thes...