giant unilamellar vesicles (guvs) consisting in self-closed lipid bilayers of 0.5-100 µm diameter are considered as oversimplified models of cells because of their biological membrane and micrometric size while large unilamellar vesicles (luvs) of 100-500 nm diameter have applications in drug delivery. to improve structural and mechanical properties of these vesicles, we have developed two cate...

This study investigated factors associated with the longevity of resin composite restorations, which were placed in 97 patients (mean age of 58 years) by 24 dentists in Nagasaki University Hospital between 1995 and 2005. All patients were under the charge of the principal investigator (SK) and most of them had been regularly checked up for up to 11 years. A total of 503 resin composite restorat...

The in silico prediction of the functional consequences of mutations is an important goal of human pathogenetics. However, bioinformatic tools that classify mutations according to their functionality employ different algorithms so that predictions may vary markedly between tools. We therefore integrated nine popular prediction tools (PolyPhen-2, SNPs&GO, MutPred, SIFT, MutationTaster2, Mutation...

statement of the problem: the bond strength of composites with different adhesive systems with dentin is an important factor in long term durability of composite restorations. the effect of titanium tetrafluoride (tif4) as anti caries agent and sodium hypochlorite (naocl) as disinfectant on the shear bond of nanofilled and silorane based composite resins have not been investigated in previous s...

car body lightening and crashworthiness are two important objectives of car design. due to their excellent performance, composite materials are extensively used in the car industries. in addition, reducing the weight of vehicle is effective in decreasing the fuel consumption. hat shape energy absorber is used in car’s doors for side impact protection. the aim of these numerical models and exper...

objectives: to assess the effect of lactic acid (la) on microleakage of silorane-based composite restorations and methacrylate-based composites with self-etch and etch-and-rinse bonding systems. materials and methods: class v cavities were prepared in 120 extracted human teeth, divided into four groups and restored as follows: 1. silorane-based composite+p90 adhesive system (p90); 2. filtek z25...

objectives: this study aimed to assess the effect of re-etching of desensitized dentin for five and 10 seconds on marginal microleakage of composite restorations. materials and methods: class v cavities (4x2x2mm) were prepared on the buccal surfaces of 64 third molars and randomly divided into four groups of 16. in the control group, single bond (sb) adhesive was applied after etching. in bb+sb...

2 D;VProvide a summary of objectives, study design,setting, participants, sample size, predictors,outcome, statistical analysis, results, andconclusionsIntroduction Background andObjectives3a D;VExplain the medical context (including whetherdiagnostic or prognostic) and rationale fordeveloping or validating the multivariableprediction model, inclu...

polymerization contraction may produce defects in the composite - tooth bond. this may lead to bond failure and microleakage. the aim of this study was to reduce microleakage of posterior composites using different methods. 45 molar and premolars extracted teeth were choosen. the cavities were randomly assigned into 5 groups of 9. box-shaped cavities were prepared on each side of proximal surfa...