Optogenetic gene switches allow gene expression control at an unprecedented spatiotemporal resolution. Recently, light-responsive transgene expression systems that are activated by UV-B, blue, or red light have been developed. These systems perform well on their own, but their integration into genetic networks has been hampered by the overlapping absorbance spectra of the photoreceptors. We ide...

A highly radiation-resistant member of the Moraxella-Acinetobacter group, isolate 4, obtained from meat, was studied to determine the effect of preexposure to UV radiation on subsequent UV light resistance. Cultures that were preexposed to UV light and incubated for a short time in plate count both exhibited increased survival of a UV light challenge dose. This response was inhibited in the pre...

1. The amount of visible or long ultraviolet light (UV) required to photoreactivate Colpidium colpoda injured with known dosages of short UV (2654 A) was determined. 2. The effect of the short UV was tested by the delay in division of exposed animals compared to controls. Photoreactivation was tested by the effect of postillumination on the delay of division of treated colpidia compared to cont...

The induction of nicotinamide adenine dinucleotide phosphate-malic enzyme (NADP-ME) in etiolated maize (Zea mays) seedlings by UV-B and UV-A radiation, and different levels of photosynthetically active radiation (PAR, 400-700 nm) was investigated by measuring changes in activity, protein quantity and RNA levels as a function of intensity and duration of exposure to the different radiations. Und...

We present a complete sample of International Ultraviolet Explorer and Hubble Space Telescope ultraviolet (UV) spectra of Type Ia supernovae (SNe Ia) through 2004. We measure the equivalent width (EW) and blueshifted velocity of the minimum of the one strong UV feature, Fe II λ3250. We also quantify the slope of the near-UV spectra using a new parameter, the “UV ratio.” We find that the velocit...

Epidemiological evidence is accumulating that beta-human papillomaviruses (HPV) synergize with UV-light in the development of precancerous actinic keratosis, and cutaneous squamous cell carcinomas (cSCC), one of the most common cancers in the Caucasian population. We previously demonstrated the tumorigenic activity of beta-HPV type 8 (HPV8) in the skin of transgenic mice and its cooperation wit...

Photochromic molecules can be switched by different absorbance spectra. Typically only one form absorbs light in the visible wavelength range and is therefore called the colored form, the other form is called transparent, and both forms absorb light in the UV wavelength range. Switching from the transparent to the colored form occurs by illumination with UV light, the back switching from colore...

Plants monitor changes in the ambient light environment using sensory photoreceptor families: the phototropins and cryptochromes, which absorb UV-A or blue light; the phytochromes, which sense red/far-red light; and the UV-B photoreceptors, which have not yet been identified. Recent advances suggest that photoreceptor-induced signalling cascades regulate light-modulated gene expression. These r...

OBJECTIVE Analysis of the crosslink time, depth and efficacy profiles of UV-light-activated corneal collagen crosslinking (CXL). METHODS A modeling system described by a coupled dynamic equations are numerically solved and analytic formulas are derived for the crosslinking time (T*) and crosslinking depth (z*). The z-dependence of the CXL efficacy is numerically produced to show the factors c...

We present a complete sample of International Ultraviolet Explorer and Hubble Space Telescope ultraviolet (UV) spectra of Type Ia supernovae (SNe Ia) through 2004. We measure the equivalent width (EW) and blueshifted velocity of the minimum of the one strong UV feature, Fe II λ3250. We also quantify the slope of the near-UV spectra using a new parameter, the “UV ratio.” We find that the velocit...