Uterine leiomyomata (fibroids) are the commonest benign pelvic tumours. Therapeutic options include hormone manipulation or surgical management, myomectomy if the patient wishes to retain fertility, or hysterectomy. We describe the use of transcatheter arterial embolisation in a patient who presented with a large uterine fibroid and pressure symptoms. CASE REPORT A forty-two year old female pat...

BACKGROUND Chinese medicine is commonly used and covered by health insurance to treat symptoms of uterine fibroids in Taiwan. This retrospective cohort study compared the consumption of conventional western medicine and medical cost between Chinese medicine (CM) users and nonusers among patients with uterine fibroids. METHODS We extracted 44,122 patients diagnosed with uterine fibrosis betwee...

Aim. To determine if hormonal treatment induces apoptosis in uterine fibroids. Methods. Immunohistochemical examination of fibroid tissue, using avidin-biotin complex and cleaved caspase-3 antibody for detecting apoptosis, was performed in premenopausal women who underwent 12-week treatment with oral SPRM (6 patients with 5 mg and 5 patients with 10 mg of ulipristal acetate per day) or gonadoli...

BACKGROUND A number of noninvasive alternatives to hysterectomy have become available as treatments for uterine fibroids. These alternative therapies, however, may not relieve all symptoms. Consequently, the need for patient-reported outcomes to assess symptom reduction of uterine fibroids has become increasingly important to evaluate the clinical success of patients who choose these alternativ...

INTRODUCTION A large number of hysterectomies are carried out for uterine prolapse, menorrhagia and other symptomatic but benign gynaecological conditions, which has increased interest in new approaches to treat these disorders. These new procedures are less invasive and offer reduced risk and faster recovery. CASE PRESENTATION Sacrohysteropexy can be carried out instead of vaginal hysterecto...

Parasitic fibroids are generally diagnosed incidentally at the time of surgery performed for symptomatic uterine fibroids. Torsion of a parasitic fibroid causing severe acute onset pain is extremely rare. We report a torsed parasitic fibroid in a patient who underwent hysterectomy using power morcellation for specimen retrieval. A 40-year-old patient with a history of laparoscopic supracervical...

Uterine fibroids may be encountered with pregnancy and many obstetricians will inevitably confront the dilemma of how best to manage fibroids causing complications in a gravid uterus. We describe two cases of unavoidable caesarean myomectomy and myomectomy performed for the management of complications during pregnancy.

The content of estrogen and progesterone receptors (ER, PR) is higher in fibroid tissue than in homologous myometrium, and both receptors seem to be regulated by the levels of circulating sex steroids. Myometrial and fibroid tissues were recovered from women undergoing gynecological operations during different phases of the menstrual cycle and during treatment with an analogue of GnRH (GnRHa). ...

Background: Leiomyoma are benign smooth muscle neoplasm’s that typically originate from the myometrium. The main objective was to evaluate the outcome of conservative surgical approach for submucous fibroid uterus is using prostaglandin preoperatively and gonadotropin releasing hormone (GnRh) in preoperative phase. Methods: Thirty eight patients who had hysteroscopic myomectomy with a resectosc...

OBJECTIVE The aim of this study was to evaluate the effect of short-term use of selective progesterone receptor modulator (SPRM) or gonadotropin-releasing hormone (GnRH) agonist on uterine fibroid shrinkage among Korean women. METHODS This retrospective study involved 101 women with symptomatic uterine fibroids who received ulipristal acetate (SPRM, n=51) and leuprolide acetate (GnRH agonist,...