A low molecular weight beta(2)-globulin (beta(2)-microglobulin), albumin, and total protein were measured in concentrated 24-hr urine specimens from 20 healthy subjects and 30 patients with clinical proteinuria of glomerular or tubular type. Classification of proteinuria was made on the basis of clinical diagnosis and size distribution of urinary proteins after gel chromatography. The molecular...

et al., 1967; Zorab et al., 1970). Allison, Walker, and Smith (1966) showed that the ratio of total hydroxyproline to creatinine in a 24-hour collection of urine gives more consistent results than measurement of hydroxyproline alone, an observation which has been extended to random samples of urine collected during waking hours (Howells, Wharton, and McCance, 1967; Younoszai et al., 1969). Whar...

PURPOSE Microalbuminuria is defined as increased urinary albumin excretion (30-300 mg/day) or microalbumin/creatinine ratio (30-300 mg/g) in a spot urine sample. Although microalbuminuria is a predictor of clinical nephropathy and cardiomyopathy, few studies have investigated microalbuminuria in children with urinary tract infection (UTI). METHODS Therefore, we compared the spot urine microal...

Random urine samples of 352 children in the age group of 5-12 yrs were studied for urinary calcium-creatinine ratio (Uca/Ucr mg/mg). None had any predisposing factor for secondary hypercalciuria. Calcium and creatinine both were estimated by colorimetric method. We observed that Uca/Ucr in the general pediatric population was skewed, the pattern was similar to that described in western children...

et al., 1967; Zorab et al., 1970). Allison, Walker, and Smith (1966) showed that the ratio of total hydroxyproline to creatinine in a 24-hour collection of urine gives more consistent results than measurement of hydroxyproline alone, an observation which has been extended to random samples of urine collected during waking hours (Howells, Wharton, and McCance, 1967; Younoszai et al., 1969). Whar...

Spot urinary albumin to creatinine ratio (ACR) measurement has been suggested as a surrogate to 24-hr urine collection for the assessment of microalbuminuria, and cystatin C (cysC) is known as an advantageous marker for renal function. The aim of this study was to evaluate the clinical values of spot urinary ACR and serum cysC for the assessment of diabetic nephropathy instead of 24-hr urine mi...