Ubiquitin-binding domains (UBDs) differentially recognize ubiquitin (ub) modifications. Some of them specifically bind mono-ub, as has been shown for the CUE domain. Interestingly, so far no significant ubiquitin binding has been observed for the CUE domain of yeast Cue1p. Cue1p is receptor and activator of the ubiquitin-conjugating enzyme Ubc7p. It integrates Ubc7p into endoplasmic reticulum (...

Drilling into a rock massif is energetically extremely consumptive process. Hence the optimization of drilling regime with objective of energy consumption minimization, is very important. Proposed article discusses partial problem of this problem. During the drilling process it is useful to know the drilled rock type, whereas to particular drilled rock needs convenient drilling regime, which is...

A virtual teeth drilling system whose basic aim is to be used for the training of dental students in the handling of drilling instruments is presented in this paper. A 3D model of the face and the oral cavity is utilized by the application. This model can be adapted to the characteristics of a specific person and animated. Drilling is performed within the oral cavity, on realistic teeth models ...

vibratory drilling (vd)process is a new modern technology where longitudinal wave with high frequency (more than 16 khz) and low amplitude (usually between 2 up to 30 µm) is superimposed on the movement of cutting tool, resulting in connection and disconnection of cutting tool engagement with workpiece. in this study, in order to perform vibratory drilling process, two vibration tools are desig...

Drilling consists of 2 processes: breaking the formation with a bit and removing the drilled cuttings. In rotary drilling, rotational speed and weight on bit are used to control drilling, and the optimization of these parameters can markedly improve drilling performance. Although fluids are used for cuttings removal in terrestrial drilling, most planetary drilling systems conduct dry drilling w...

OBJECTIVES The purpose was to assess thermal changes and drill wear in bovine bone tissue with the use of twisted stainless steel and zirconia-based drills, during implant site preparation. METHODS A total of 100 implant site preparations were performed on bovine ribs using a surgical unit linked to a testing device, in order to standardize/simulate implant drilling procedures. Bone temperatu...

Inconel 718 is considered the most widely adopted nickel-based superalloy, and drilling of this alloy always challenging for researchers. Cemented carbide twist drills have been evaluated in by changing cutting environment or varying tool geometry. In latter case, speed has extended from 30 m/min to 60 when are micro-textured ground. study, contrary cemented drills, first time, inserts named st...

Antegrade transmalleolar drilling method is one of the options for the treatment of osteochondral lesion of talus (OLT). We present five patients who underwent tibial drilling for treatment of OLT and later developed distal tibial cystic formation induced by cartilage opening or heat necrosis during drilling. Antegrade transmalleolar drilling can be a possible option for the treatment of OLT if...

BACKGROUND Optimal tunnel placement is critical in anterior cruciate ligament reconstructive surgery, yet the method used to drill the tunnels may compromise their placement. HYPOTHESIS An independent drilling method versus a conventional transtibial drilling method will place tunnels in different locations and produce reconstructions with different kinematics. STUDY DESIGN Controlled labor...

Currently, the drilling fluid processing and recycling has gained more attention from various oilfields. Whether the waste drilling fluid’s processing and recycling is good or not will directly affect the development of oil industry. Therefore, the urgent affair is to develop and research the processing method of waste drilling fluid.This article describes various processing methods of waste dr...