BACKGROUND Non-variceal upper gastro-intestinal bleeding (NVUGIB) is a common and challenging emergency situation. We aimed to describe the characteristics and clinical outcomes of patients with NVUGIB in Greece. METHODS ENERGIB (NCT00797641) was an epidemiological survey conducted in 7 European countries including Greece. It included adult patients with overt NVUGIB from 10 tertiary hospital...

Extended treatment with vitamin K antagonists for more than 6 months is often used for secondary prevention of venous thromboembolism (VTE) in patients at high or moderate risk for recurrent events. The intensity of anticoagulant therapy is usually maintained at an International Normalized Ratio (INR) of 2-3. An INR of 1.5-2 might also prevent thromboembolic events with less complications of bl...

BACKGROUND The coagulopathy of trauma is generally confirmed by prothrombin time (PT) > or =16 seconds or an international normalized ratio > or =1.5. However, the utility of these values as a screening test is unknown. We examined different coagulation tests to determine the best predictor of coagulopathic bleeding and mortality in a small animal hemorrhage model. METHODS Coagulopathy was in...

UNLABELLED In this randomized, controlled study in dogs, we examined the short-term effects of blood pressure targeted fluid resuscitation with colloids or crystalloids solutions on systemic oxygen delivery, and lactate blood concentration. Fluid resuscitation using hydroxyethyl starch (HES) 6% to a mean arterial blood pressure (MAP) of 60 mm Hg was compared with lactated Ringer's solution (LR)...

Background: Patients with advanced head and neck cancers typically succumb to uncontrolled local disease. Even aggressive therapy, median survival is about 12 months, the five-year overall <20%. Radiation treatment used in palliative setting an option for some patients who are not eligible curative therapy. Palliative aims reduce cancer-related symptoms while causing fewest side effects toxi...

background: one of the biggest problem today that most developing countries are faced with is the uncontrolled population growth; a serious threat to the international community. one of the most accessible contraceptive methods is the hormonal methods in which low-dose estrogen (ld) combined pills are considered as the most common among them. the most important reason for discontinuation of the...

Background: a recurrence of stroke, is matter concern because it can worsen the situation, increase treatment costs, and death risk. Stroke caused by multifactorial cases. The objective this study to analyze factors associated with stroke in university muhammadiyah malang hospital. Methods: This used cross-sectional observation analytic study. A total sample 64 people was collected using purpos...

BACKGROUND Hypertension affects 30% of adults worldwide. Garlic supplements have shown promise in the treatment of uncontrolled hypertension, and the mechanism of action is biologically plausible. Our trial is the first to assess the effect of aged garlic extract on central blood pressure and arterial stiffness, regarded as important risk factors for cardiovascular morbidity. SUBJECTS AND MET...

BACKGROUND The appropriateness of vigorous fluid resuscitation to normal blood pressure following hemorrhage in uncontrolled bleeding has recently been questioned due to the possibility of dislodging clots and exacerbating hemorrhage. To develop a rational blood pressure target that maximizes the metabolic benefits of resuscitation without causing increased blood loss, it was first necessary to...