BACKGROUND Positron emission tomography studies in human subjects show that propofol-induced unconsciousness in humans is associated with a reduction in thalamic blood flow, suggesting that anaesthesia is associated with impairment of thalamic function. A recent study showed that antagonism of propofol-induced unconsciousness by the anticholinesterase physostigmine is associated with a marked i...

Since CT scans make it possible to demonstrate precise morphological and anatomico pathological findings, small brain lesions are frequently found on CT scans, in spite of the short duration of unconsciousness after head trauma. Thirty six out of approximately 500 cases which received CT examinations within two weeks after head injury were selected and analyzed. In these cases, almost all high ...

Recent researches indicate that the mechanism of anesthetic induce loss of consciousness (LOC) is related to dopamine dysfunction in the media prefrontal cortex (mPFC). Given GABAA receptors are the main target for commonly intravenous anesthetic propofol, in this study, we test whether that propofol induced LOC mediate by GABAA receptors in mPFC through altering the dopamine and its metabolite...

The author is carrying out technology studies to explore and expand human emotions, sensibility, and consciousness by making innovative use of artistic creativity. We develop interfaces for experiencing and expressing the "essence of culture'' such as human feelings, ethnicity, and story. History has shown that human cultures have common and unique forms such as behavior and grammar. We suggest...