Cyclocarya paliurus (Batal.) Iljinskaja (LCP) leaves have been widely employed in food and traditional medicine for treating hyperlipidaemia its complications, possibly owing to their antioxidant properties. The aim of the present study is identify chemical ingredients extracts from LCP by using UHPLC-Q-Orbitrap-MS/MS-based molecular networking, a very recent useful tool annotation constituents...

Terminalia catappa and subspathulata are two species of the Combretaceae family medium to large forest trees. The fruits T. known for edible nuts commonly as tropical almonds due their similarity in taste with commerce. Therefore, chemical profiles were examined ascertain potential value food or health uses. Gas chromatography-mass spectrometry (GCMS) ultrahigh-pressure liquid chromatography-el...

An efficient and rapid affinity-based screening method for directly fishing out natural alpha-glucosidase inhibitors from Cyperus. rotundus extract by using immobilized enzyme technology combined with UHPLC-QTOF MS analysis was established. As a results, without time-consuming and laborious isolation workload and false positive interference, five natural alpha-glucosidase inhibitors were succes...

A new class of N-linked protein glycosylation - arginine rhamnosylation - has recently been discovered as a critical modification for the function of bacterial elongation factor P (EF-P). Herein, we describe the synthesis of suitably protected α- and β-rhamnosylated arginine amino acid "cassettes" that can be directly installed into rhamnosylated peptides. Preparation of a proteolytic fragment ...

UHPLC-DAD-HRMS based dereplication guided the detection of new halogenated alkaloids co-produced by Talaromyces wortmannii. From the fungal growth in large scale, the epimers 2,8-dichlororugulovasines A and B were purified and further identified by means of a HPLC-SPE/NMR hyphenated system. Brominated rugulovasines were also detected when the microbial incubation medium was supplemented with br...

A fast and effective UHPLC/QTOF‐MS method using a simple methanol extraction has been developed to determine the structural characteristics of steroidal saponins from dried rhizomes of two Dioscorea species (D. villosa L. and D. cayenensis Lam.) and dietary supplements. The saponins were identified or tentatively characterized from their retention times and mass spectra and the fragmentation pa...

A rapid and sensitive ultra-high-performance liquid chromatography-electrospray ionization quadrupole time of flight mass spectrometry (UHPLC-ESI-QTOF-MS) based method was developed to separate identify 44 phenolics non-phenolics present in Averrhoa carambola fruit three different stages its growth. 5 anthocyanins, 9 phenolic acids, 3 flavones, flavanols, flavanones, amino vitamins other non-ph...

The ability of a contemporary accurate-mass Q-TOF instrument coupled to a UHPLC to detect trace levels of nonylphenol polyethoxylates (NPEOs) in complex wastewaters has been investigated. NPEOs are environmentally hazardous substances that affect aquatic organisms. The study was motivated by the “confirmation of contaminants” concept, which is based on the use of identification points (IPs) as ...

A rapid, sensitive and selective analysis method using Ultra High Performance Liquid Chromatography coupled to triple-quadrupole Mass Spectrometry (UHPLC-QqQ-MS) has been developed for the quantification of polyphenols in rosé wines. The compound detection being based on specific MS transitions in Multiple Reaction Monitoring (MRM) mode, the present method allows the selective quantification of...