OBJECTIVE The presence of an enhanced cortisol secretion in patients with type 2 diabetes is debated. In type 2 diabetic subjects, cortisol secretion was found to be associated with the complications and metabolic control of diabetes. We evaluated cortisol secretion in 170 type 2 diabetic subjects and in 71 sex-, age-, and BMI-matched nondiabetic subjects. RESEARCH DESIGN AND METHODS In all s...

OBJECTIVE The diagnosis of Cushing's syndrome (CS) remains a challenge in clinical endocrinology. The aim of this study was to determine the reproducibility and diagnostic value of late-night salivary cortisol (SAF(23)) for CS and its utility along the follow-up of treated patients. In addition, using the same radioimmunoassay reactives, the cut-off values for saliva and serum cortisol, assesse...

OBJECTIVE The aim of the study was to evaluate the relationship between cortisol secretion, bone health, and bone loss in a cohort of normal women in the early postmenopausal period. METHODS We measured lumbar and hip bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA) and heel ultrasound parameters in 82 healthy, nonosteoporotic (lumbar T-score ≥-2.0) women (median age 52.5 ...

BACKGROUND In subclinical Cushing syndrome (SC), it is assumed that glucocorticoid production is insufficient to cause a clinically recognizable syndrome. Differences in hormonal levels or recovery time of the hypothalamic-pituitary-adrenocortical (HPA) axis after adrenalectomy between patients with overt Cushing syndrome (OC) and SC remain unknown. METHODS Thirty-six patients (10 with OC and...

OBJECTIVE Several tests have been proposed to diagnose patients with Cushing's syndrome (CS). The aims of the study were: i) to evaluate the performance of salivary cortisol (SC) in hypercortisolism and ii) to compare SC with serum cortisol (SeC) and urinary cortisol. DESIGN AND PATIENTS This was a diagnostic study. Twenty-seven patients with untreated Cushing's disease (CD untr), 21 women co...

Introducción: las soluciones multipropósito (SMP) para lentes de contacto blandos (LCB) desempeñan un papel esencial en la inhibición agentes patógenos. Su efectividad antimicrobiana se evalúa in vitro, y su seguridad, vivo, con ensayos clínicos que incluyen una combinación diferentes materiales lentes. El objetivo es evaluar biocompatibilidad nueva SMP producida Colombia contiene polihexametil...

En el fomento de nuevas plantaciones cafeto, un elemento decisivo es empleo posturas vigorosas. El objetivo esta investigación fue evaluar efecto productos bioestimulantes sobre la germinación café arábigo (Coffea arabica L.) var. Sarchimor y posible estos tratamientos posterior crecimiento las plántulas en vivero. material siembra empleado semillas variedad C-1669. Se evaluaron tres bioestimul...