This work develops a morphing concept that utilises metamaterial as the passive device for helicopter blades. The metamaterials are created with bend–twist coupling, which enable blade twist under prescribed bending loads. Finite element analysis (FEA) is performed to investigate influence of unit cell configurations on coupling properties metamaterials. numerical models then validated experime...

Patients with low-grade myelodysplastic syndromes (MDS) show high levels of tumor necrosis factor α (TNFα) and up-regulation of apoptosis in the marrow. In contrast, marrow cells in advanced MDS are typically resistant to TNFα-induced apoptosis but are rendered apoptosis-sensitive on coculture with stroma. The present studies show that CD34(+) marrow cells in advanced MDS express high levels of...

Sutural growth depends on maintenance of a balance between proliferation of osteogenic stem cells and their differentiation to form new bone, so that the stem cell population is maintained until growth of the skull is complete. The identification of heterozygous mutations in FGFR1, -2 and -3 and TWIST as well as microdeletions of TWIST in human craniosynostosis syndromes has highlighted these g...

Androgen-independent metastatic prostate cancer is the main obstacle in the treatment of this cancer. Unlike a majority of solid cancers, prostate cancer usually shows poor response to chemotherapeutic drugs. In this study, we have shown a potential novel target, TWIST, a highly conserved bHLH transcription factor, in the treatment of prostate cancer. Using malignant and nonmalignant prostate t...

One of the first steps in embryonic mesodermal differentiation is allocation of cells to particular tissue fates. In Drosophila, this process of mesodermal subdivision requires regulation of the bHLH transcription factor Twist. During subdivision, Twist expression is modulated into stripes of low and high levels within each mesodermal segment. High Twist levels direct cells to the body wall mus...

Patients with low-grade myelodysplastic syndromes (MDS) show high levels of tumor necrosis factor (TNF ) and upregulation of apoptosis in the marrow. In contrast, marrow cells in advanced MDS are typically resistant to TNF -induced apoptosis but are rendered apoptosissensitive on coculture with stroma. The present studies show that CD34 marrow cells in advanced MDS express high levels of TWIST,...

We investigate the twist-3 effects in the polarized virtual photon structure. The structure functions g 1 and g γ 2 of polarized photon could be experimentally studied in the future polarized ep or ee colliders. The leading contributions to g 1 are the twist-2 effects, while another structure function g 2 , which only exists for the virtual photon target, receives not only the twist-2 but also ...

Introduction Left ventricular (LV) twist is believed to store potential energy and plays an important role in generating diastolic suction. Recent advances in echocardiography techniques have allowed quantification of LV twist. The aim of the present study was to compare LV twist and torsion in healthy human subjects determined by velocity vector imaging (VVI) and tissue Doppler imaging (TDI) a...

‎‎in the category of mordell curves (e_d:y^2=x^3+d) with nontrivial torsion groups we find curves of the generic rank two as quadratic twists of (e_1), ‎and of the generic rank at least two and at least three as cubic twists of (e_1). ‎previous work‎, ‎in the category of mordell curves with trivial torsion groups‎, ‎has found infinitely many elliptic curves with rank at least seven as sextic tw...

The purpose of introducing ultrasonic vibrations in the tube hydroforming process is to create more formability by obtaining a lower corner radius, improve thickness distribution of the wall and provide good tribological conditions at the tube and the die interface. Vibrations imposed on the die create alternating gaps which improve the formability in the tube hydroforming process in the presen...