نتایج جستجو برای: tumor angiogenesis
تعداد نتایج: 454475 فیلتر نتایج به سال:
Since the relationship between angiogenesis and tumor growth was established by Folkman in 1971, scientists have made efforts exploring the possibilities in treating cancer by targeting angiogenesis. Inhibition of angiogenesis growth factors and administration of angiogenesis inhibitors are the basics of antiangiogenesis therapy. Transfer of anti-angiogenesis genes has received attention recent...
Chronic inflammation is associated with the metastasis of tumor cells evolving from a benign tumor to disseminating cancer. Such a metastatic progression is fostered by the angiogenesis propelled by various mediators interacting at the site of tumor growth. Angiogenesis causes two major changes that are assisted by altered glycosylation and neo-antigen presentation by the cancer cells. The angi...
Galway, Ireland Fibroblasts Influence Angiogenesis in Tissue Regeneration Susana Guerreiro, Rita Negrão, Maria J. Oliveira, Mário A. Barbosa, Raquel Soares, Pedro L. Granja Corresponding Author: [email protected] 1 INEB Instituto de Engenharia Biomédica, Universidade do Porto (U.Porto), Porto, Portugal, 2 Faculdade de Medicina (U.Porto), Dept. Bioquímica (U38-FCT), Porto, Portugal 3 Faculdade d...
Angiogenesis promotes tumor development. Understanding the crucial factors regulating tumor angiogenesis may reveal new therapeutic targets. Human GT198 (PSMC3IP or Hop2) is an oncoprotein encoded by a DNA repair gene that is overexpressed in tumor stromal vasculature to stimulate the expression of angiogenic factors. Here we show that pericytes expressing GT198 give rise to tumor cells through...
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