Abstract Background Recent studies have established the roles of microRNAs (miRNAs) in cancer progression. The aberrant expression miR-335-5p has been reported many cancers, including gastric (GC). In this study, precise GC as well molecular mechanisms underlying its effects, role target MAPK10, were evaluated. Methods Quantitative real-time PCR was used to evaluate levels cell lines and tissue...

TABLE OF CONTENTS PAGE INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335 Are the agglutinogens M and N linked to A and B ? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 Derivation of formula for Q., . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Derivation of f...

Atopic dermatitis (AD) is a chronic inflammatory skin disorder which characterized by intense itch and eczematous lesions. Keratinocytes are pivotal cells in the pathogenesis of AD as much Th2 cells. Regulation pro-inflammatory features keratinocytes combination with T cell modulators such JAK inhibitors might hold promise for achieving disease control patients better than alone. In this regard...

the aim of this study was to design orally disintegrating tablets of olanzapine and to complex olanzapine with 2-hydroxypropyl-β- cyclodextrin with special emphasis on disintegration and dissolution studies. phase solubility studies demonstrated the formation of 1:1 molar inclusion complex by kneading method. tablets were prepared by using superdisintegrants namely, sodium starch glycolate, cro...