Screening for tuberculosis in high-prevalence countries relies on sputum smear microscopy. We present a method for the automated identification of Mycobacterium tuberculosis in images of Ziehl-Neelsen-stained sputum smears obtained using a bright-field microscope. We use two stages of classification. The first comprises a one-class pixel classifier for object segmentation. Geometric transformat...

Background: Case Notifivation Rate (CNR) is one of survailance tuberculosis (TB) program goals indicator in public health centre which indicate the discovery rate new patients society, however Denpasar City TB CNR last three years (2011-2013) tends to decrease. Aims study: for implementation and evaluation case screening activities with DM (Diabetes Melitus) Public Health Centres. Method: Imple...

Tuberculosis is most common during a woman’s generative years and is a chief cause of maternal–child mortality. Tuberculosis (TB) remains a fundamental infection in women globally. Therefore the screening of the pregnant women should be done. The present study was planned to study the prevalence of tuberculosis infection among pregnant women. The study was done in the gynecology department amon...

STUDY OBJECTIVE To determine if screening by specialists could reduce unnecessary test ordering and reduce costs related to diagnostic workup in patients undergoing evaluation for tuberculosis. DESIGN Prospective evaluation of expert opinion in consecutive patients suspected of having tuberculosis. SETTING A large municipal hospital. PATIENTS Patients for whom sputum acid-fast smears were...

Background Chest radiography (chest X-ray or CXR) plays an important role in the early detection of active pulmonary tuberculosis (TB). In areas with a high TB burden that require urgent screening, there is often shortage radiologists available to interpret results. Computer-aided (CAD) software employed artificial intelligence (AI) systems may have potential solve this problem. Objective We va...

A simple and cost-effective diagnostic tool (TB Screen Test) for the screening of patients with pulmonary and extrapulmonary tuberculosis and for differentiation of those individuals from individuals without tuberculosis, other common infections, and healthy controls has been developed. The serological responses of purified mycobacterial glycolipid antigens were examined by a liposome agglutina...

Mycobacterium tuberculosis remains one of the world's most devastating pathogens. For this reason, we developed a study involving 3D pharmacophore searching, selectivity analysis and database screening for a series of anti-tuberculosis compounds, associated with the protein kinases A, B, and G. This theoretical study is expected to shed some light onto some molecular aspects that could contribu...

The total blood lymphocyte proliferation assay (TLP) was evaluated as a screening test for infection with Mycobacterium tuberculosis and was compared with the tuberculin (Mantoux) skin test. The results of TLP assays performed on 33 patients with tuberculosis and 37 non-tuberculous subjects were compared with results of skin tests performed in the previous year. There was a high correlation bet...

Abstract In clinical settings where airborne pathogens, such as Mycobacterium tuberculosis, are prevalent, they constitute an important threat to health workers and people accessing healthcare. We report key insights from a 3-year project conducted in primary healthcare clinics South Africa, alongside other recent tuberculosis infection prevention control (TB-IPC) research. discuss the fragment...

BACKGROUND Close contacts of tuberculosis (TB) patients are at increased risk of developing tuberculosis. Although passive contact screening guidelines are incorporated in the national TB control program, currently it is unknown how frequent close contacts are screened for TB in Vietnam. This study assesses current contact screening practices in Vietnam and determines the proportion of househol...