Previous reports highlight the role of systemic inflammation in the genesis of non-thyroidal illness syndrome and type 2 diabetes mellitus (T2DM). Our objective was to assess whether body mass index and the low-grade systemic inflammation would be associated with changes in thyroid hormone metabolism in patients with type 2 diabetes. This was a cross-sectional study of 104 subjects; 52 patients...

The aim of the present study is to use Fourier transform infrared spectrometry (FTIR), and transmission electron microscopy (TEM) techniques, to make a more detailed description of toxic effects of 3,3',4,4',5-pentachlorobiphenyl (PCB126) on bone tissue at the microstructural and at the molecular level as a result of an altered bone metabolism. We have analysed potential changes on vitamin D an...

OBJECTIVE Deficiencies of vitamin A and iodine are common in many developing countries. Vitamin A deficiency (VAD) may adversely affect thyroid metabolism. The study aim was to investigate the effects of concurrent vitamin A and iodine deficiencies on the thyroid-pituitary axis in rats. DESIGN Weanling rats (n = 56) were fed diets deficient in vitamin A (VAD group), iodine (ID group), vitamin...

BACKGROUND Perfluoroalkyl acids (PFASs) are suspected thyroid toxicants, but results from epidemiological studies are inconsistent. OBJECTIVES We examined associations between serum PFASs and thyroid hormones (THs) in a representative, cross-sectional sample of U.S. adults. We hypothesized that people with high thyroid peroxidase antibodies and low iodine would be more susceptible to PFAS-ind...

Introduction: Verapamil, a phenylalkylamin –type Ca2+ channel blocker, is widely used in the treatment of cardiovascular disorders especially as an antiaryhthmic and antiangina agent. Theoretically, calcium can influence thyroid function and there are evidences that Ca2+ channel blockers are able to interfere with thyroid function. In this study, the effects of chronic oral administration of...

introduction: verapamil, a phenylalkylamin –type ca2+ channel blocker, is widely used in the treatment of cardiovascular disorders especially as an antiaryhthmic and antiangina agent. theoretically, calcium can influence thyroid function and there are evidences that ca2+ channel blockers are able to interfere with thyroid function. in this study, the effects of chronic oral administration of ve...

The solution is given for the c = 3 topological matter model whose underlying conformal theory has Landau-Ginzburg model W = − 4 (x + y)+αxy. While consistency conditions are used to solve it, this model is probably at the limit of such techniques. By using the flatness of the metric of the space of coupling constants I rederive the differential equation that relates the parameter α to the flat...

The sensitive and tightly regulated feedback control system, thyroid gland autoregulation, and the large intrathyroidal and extrathyroidal storage pools of thyroid hormone serve to provide a constant supply of thyroid hormone to peripheral tissues in the face of perturbations imposed by the external environment, chemicals and drugs, and a variety of diseases processes. The thyroid is subject to...